Guided Radiotherapy

Dec 25, 2017 by in ONCOLOGY Comments Off on Guided Radiotherapy

Fig. 1 a CT scan of the brain. b MR scan of the brain. There are two small metastatic lesions clearly visible in the MR scan that are invisible in the…

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and Image Guided Systemic Radiotherapy

Dec 25, 2017 by in ONCOLOGY Comments Off on and Image Guided Systemic Radiotherapy

Fig. 1 Select examples of radiation dose-toxicity curves demonstrating that a reduction in dose to normal organs is associated with a decrease in late organ toxicities such as pneumonitis, nephritis and…

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Modeling in Radiation Oncology

Dec 25, 2017 by in ONCOLOGY Comments Off on Modeling in Radiation Oncology

where α (1/Gy) and β (1/Gy2) are parameters that determine the shape of the curve. Indeed, a vast literature exists on the mechanistic and empirical history of this famous equation,…

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Stem Cells and Tumor Microenvironment in Radiotherapy

Dec 25, 2017 by in ONCOLOGY Comments Off on Stem Cells and Tumor Microenvironment in Radiotherapy

Fig. 1 Representative images showing the different acini structures generated from immortalized normal human breast epithelial MCF10A, breast cancer MCF7 and BCSCs isolated from MCF7 population that survived a course of…

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and Hypofractionation for Primary Tumors

Dec 25, 2017 by in ONCOLOGY Comments Off on and Hypofractionation for Primary Tumors

Fig. 1 External compression was one of the first techniques used to address tumor motion in lung SBRT Fig. 2 Image guidance with CBCT prior to delivery was sufficient to provide treatment…

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Mammalian DNA Damage Response as a Target for Therapeutic Gain in Radiation Oncology

Dec 25, 2017 by in ONCOLOGY Comments Off on Mammalian DNA Damage Response as a Target for Therapeutic Gain in Radiation Oncology

© Springer International Publishing AG 2017Jeffrey Y.C. Wong, Timothy E. Schultheiss and Eric H. Radany (eds.)Advances in Radiation OncologyCancer Treatment and Research10.1007/978-3-319-53235-6_11 The Mammalian DNA Damage Response as a Target for Therapeutic Gain in Radiation…

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and Radiotherapy

Dec 25, 2017 by in ONCOLOGY Comments Off on and Radiotherapy

© Springer International Publishing AG 2017Jeffrey Y.C. Wong, Timothy E. Schultheiss and Eric H. Radany (eds.)Advances in Radiation OncologyCancer Treatment and Research10.1007/978-3-319-53235-6_10 Biomarkers and Radiotherapy Savita V. Dandapani1   (1) Department of Radiation Oncology, City of Hope, Duarte,…

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and the Treatment of Oligometastatic Disease

Dec 25, 2017 by in ONCOLOGY Comments Off on and the Treatment of Oligometastatic Disease

Publication Year Number of patients Median follow-up (months) RT dose Metastases control Overall survival University of Chicago (Wong et al. 2016) 2016 61 82 24–48 Gy in 3 fractions 44% at…

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