Highlights • Controversy remains regarding adjuvant therapy (AT) in patients treated with neoadjuvant chemotherapy (NAC) and radical cystectomy (RC) for muscle-invasive bladder cancer. • Determining variables that may affect cancer-specific…
Highlights • In the absence of evidence from randomized controlled trials, Trimodal Therapy (TMT) for muscle-invasive bladder cancer (MIBC) is usually reserved to patients with poor overall health status. •…
Highlights • Stented radical cystectomies had higher major complications ( P = 0.04); • Stentless radical cystectomy was noninferior in UIAS rate; • Stentless radical cystectomy was noninferior in UIAL rate;…
Abstract Prostate cancer is the second most diagnosed cancer and the fifth leading cause of cancer death among men worldwide. In the 1980s, the development and implementation of Prostate-Specific Antigen…
Abstract Prostate specific antigen (PSA) has transformed the diagnosis and treatment of prostate cancer by enabling early detection at global scale. Due to expression in both benign and malignant cells,…
Highlights • Family history of prostate cancer is an important risk factor of being diagnosed with the disease, even in the setting of low PSA. • Black men are at…
Highlights • Randomized trials show PSA screening decreases prostate cancer-mortality. • Adjunct tests and focus on high-risk patients will improve prostate cancer screening. • A closer look at divergence in…
Abstract Prostate cancer (PCa) screening has evolved beyond PSA and digital rectal exam to include multiparametric prostate MRI (mpMRI). Incorporating this advanced imaging tool has further limited the well-established problem…
Highlights • Prostate specific antigen is a proven screening test that has reduced prostate cancer mortality. • A desire to improve the positive and negative predictive values of PSA has…
Highlights • There is still uncertainty about PI-RADS 3 lesions. • Machine learning (ML) models are effective in biopsy decision making in PI-RADS 3 lesions. • Parameters such as SII,…
