Key points • Liver metastasis is a major cause of mortality and morbidity in patients with cancers of various origins and presents a therapeutic challenge because only a few patients…
Key points • Patients with cirrhosis are at highest risk of developing hepatocellular carcinoma (HCC) and screening with sonography every 6 months is recommended. • Early-stage HCC should be treated…
Key points • Image guided techniques are the most common invasive therapy for unresectable hepatocellular carcinoma (HCC). • Level 1 evidence supports survival benefit chemoembolization. • New embolic devices may…
Key points • Regional perfusion is a method of delivering high-dose chemotherapy to a region burdened with cancer. • Isolated limb perfusion and hepatic perfusion are traditional open surgical methods…
Key points • The treatment of colorectal cancer, metastatic to liver, should be optimally managed within the context of a multidisciplinary team to improve patient-centered outcomes. • Treatment intent should…
Key points • Although relatively rare, cholangiocarcinoma is the second most common primary hepatobiliary malignancy in the United States, and its incidence is increasing. • Surgical treatment remains the cornerstone…
Key points • The pathologic endpoint for percutaneous thermal or ethanol treatment of unresectable tumors is coagulation necrosis. Similarly, the goals of transarterial therapy are cell necrosis and apoptosis. •…
Key points • The clinical application of radiation oncology balances the dual goals of improved tumor control with reduced treatment-related morbidity. • Over time, technological and biological advances have offered…
Introduction Research in interventional radiology has historically been driven by innovation and technological development leading to the conceptualization, investigation, validation, and application of a myriad of novel procedures into clinical…
Key points • Cytotoxic chemotherapy has not proven effective in hepatocellular carcinoma (HCC). Sorafenib is the only approved agent for advanced, unresectable disease. • Current studies are evaluating a wide…
