Palliative Care
Opioid Dosage form Strength Starting doses of short-acting opioids for opioid naïve patients Morphine Oral solution Tablets ER (q12 h) Tablets ER (q 24 h) Tablets IR Injectable SC, IV,…
ONCOLOGY
Cancer of the Vulva and Vagina
Fig. 3.1. Histolopathologic Types of Carcinoma of the Vulva: SEER Data 1988–2001 [2]. Data source: Kosary CL. Cancer of the Vulva. In: Ries LAG, Young JL, Keel GE, Eisner MP,…
Epithelial Ovarian Cancer, Low Malignant Potential, and Sex Cord Stromal Tumors of the Ovary
Risk factor Nulliparity Early menarche Late menopause Increasing age White race Family history Personal history of breast cancer Hormone replacement therapya Fertility drugsa Talca aControversial Early Detection and Screening for…
Cervical Cancer
E1 E2 E4 E5 E6 E7 L1 L2 ATPase Regulator of E6 and E7 Disrupts cytokeratin matrix for release of virions Potentiation of membrane bound EGF receptors Bind and inactivate…
Uterine Corpus Cancers
Panici trial ASTEC trial #Patients 514 1408 Eligibility Clinical Stage I, >50 % myometrial invasion (excluded Stage IB grade 1), age <75, good performance status, no prior RT or…
Chemotherapy for Gynecologic Cancer
Agent Mechanism of action Toxicities Clinical pearls Paclitaxel [1, 2] Antimicrotuble agent; stabilizes microtubules inhibiting interphase and mitosis •Myelosuppression •Nausea/vomiting (low risk) •Peripheral neuropathy •Arthralgia/myalgia •Hypersensitivity •Alopecia •Vascular irritant •Should…
Dual Energy CT in Musculoskeletal Tumors
Fig. 9.1 A 56-year old man presented with bilateral medial malleolus acute pain without history of trauma. Erythrocyte sedimentation rate (ESR) was negative. There was no history of gout, malignancy,…
Dual Energy CT in Pancreatic Tumors
Fig. 6.1 A 66-year-old woman with pancreatic ductal adenocarcinoma. (a) DECT pancreatic parenchymal phase GSI server standard pancreatic carcinoma postprocessing “collage” with 70 keV (left column), 52 keV (middle column),…
Dual Energy CT: Basic Principles
(1.1) Here μ is the linear attenuation coefficient of the x-rays at point (x, y, z), L is the thickness of the tissue crossed by the x-ray beam, and s…
Dual Energy CT in Chest Tumors
Characterization of lung nodules/masses as benign or malignant Imaging in confirmed lung cancer Assessment of tumor vitality and therapy response Nodal staging Imaging pulmonary embolism in cancer patients Pulmonary perfusion…
