Fig. 1.1 Worldwide ovarian cancer incidence and mortality rates. Rates are per 100,000 and represent age-standardized rates according to the world standard population (ASR (W)) (From the International Agency for…
9. Eisenhauer EL, Abu-Rustum NR, Sonoda Y, Levine DA, Poynor EA, Aghajanian C, et al. The addition of extensive upper abdominal surgery to achieve optimal cytoreduction improves survival in patients…
(1) Institut Bergonié, Bordeaux, France Abstract Apoptosis is one of the main modalities of cell death, so important that it has outshined all others that only begin to be…
(1) Institut Bergonié, Bordeaux, France Abstract Cell cycle consists of the sequential events occurring between the emergence of a new cell and that of the two daughter cells generated…
(1) Institut Bergonié, Bordeaux, France Abstract Oxygen is, first of all, the combustive agent required for life and the provider of energy required by all heterotrophic organisms, those which…
(1) Institut Bergonié, Bordeaux, France Abstract The phosphatidylinositol 3-kinase (PI3K) pathway is one of the signalling pathways activated following the interaction of a growth factor with a tyrosine kinase…
(1) Institut Bergonié, Bordeaux, France Abstract Signalling pathways originating from the interaction between growth factors (GF) and tyrosine kinase receptors (TKRs) are certainly the best known because of their…
(1) Institut Bergonié, Bordeaux, France Abstract Toll-like receptors (TLR) constitute a family of receptors involved in immune and inflammatory processes, which recognise molecules derived from infectious agents (bacteria, viruses)…
(1) Institut Bergonié, Bordeaux, France Abstract G-protein-coupled receptors (GPCRs) constitute a huge family of membrane receptors to numerous hormones, neurotransmitters and diverse compounds. A large part of cardiovascular and…
(1) Institut Bergonié, Bordeaux, France Abstract Nuclear receptors constitute a special class of transcription factors that are activated by an extracellular signal. This signal is a hydrophobic substance, such…
