GC-MS Sensor array Compounds Volatile and semi-volatile compounds Tunable through choice of sensors Accuracy of compound identification Very high No compound identification Detection limit ~ppm v , can be…

Organization Screening recommendations AAFP Every 1–2 years, ages 50–69; counsel women ages 40–49 about potential risks and benefits of mammography and clinical breast examination ACOG Every 1–2 years starting at…

Fig. 9.1 The histogram shows the rate of increase per year in scientific publications indexed by PubMed, regarding the most frequent types of cancer: breast, lung, prostate, colon, and thyroid…

(1) Pharmaceutical Biotechnology, Faculty of Pharmacy, Anadolu University, Tepebaşı, Eskişehir, Turkey (2) Yunusemre Campus, Anadolu University, Eskişehir, Turkey (3) Anadolu University, Tepebaşı, Eskişehir, Turkey   Abstract Breast cancer, one of…

Database Curator Publication Gene Expression Omnibus (GEO) National Center for Biotechnology Information (NCBI) [111] Riken Expression Array Database (READ) Riken [112] ArrayTrack U.S. Food and Drug Administration (FDA) [113] ArrayExpress…

Fig. 11.1 Lipid structure representations. Examples of structures from the major classes of biological lipids (cholesterol, free fatty acid, triglyceride, phospholipid) are shown Living cells acquire fatty acids for their…

Fig. 17.1 Some characteristic issues of complex biological systems. We can notice that these are interdependent phenomena that cannot be treated separately, hence the need for integrative methodologies HTOTs provide…

Class Symbol Characteristic Disease/biological function associations Long intergenic noncoding RNAs lincRNAs Ranging from hundreds to tens of thousands nts; lie within the genomic intervals between two genes; transcriptional cis-regulation of…

Fig. 27.1 Comparison of overall survival and surrogate endpoints Disease-Free Survival (DFS) Disease-free survival (DFS) is defined as the time from randomization until recurrence of tumor or death from any…