ONCOLOGY

Multimodality Therapy in Gastric Cancer

Jun 4, 2017 by in ONCOLOGY Comments Off on Multimodality Therapy in Gastric Cancer

Treatment arms Primary end point Secondary end points MAGIC [3] Surgery alone Epirubicin 50 mg/m2 day 1 5-year OS 5-year PFS Cisplatin 60 mg/m2 day 1 HR 0.75 HR 0.66…

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Pathogenesis of Esophageal Cancer

Jun 4, 2017 by in ONCOLOGY Comments Off on Pathogenesis of Esophageal Cancer

Risk factor Risk Tobacco 4–8× Alcohol 1.3–8× Alcohol dehydrogenase 4× Fruits and vegetables 0.53–0.56× Poverty 8× Gastroesophageal reflux 7.7× Obesity 3.1× Helicobacter pylori infection 0.56–1.1× Squamous Cell Carcinoma Worldwide squamous…

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HCC

Jun 4, 2017 by in ONCOLOGY Comments Off on HCC

The clinical evaluation and management of HCC require a comprehensive, multidisciplinary approach that involves cancer surveillance and consideration of both surgical and medical therapies. The implementation of such an approach…

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Pharmacokinetic Aspects of Regional Tumor Therapy

Jun 4, 2017 by in ONCOLOGY Comments Off on Pharmacokinetic Aspects of Regional Tumor Therapy

PK parameter Dimension Relevance t 1/2zp Time Transfer from blood to deep compartment t 1/2el Time Elimination half-life from the body c max Concentration/volume Peak concentration in blood or tissue…

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Chemoembolization of Lung Tumors

Jun 4, 2017 by in ONCOLOGY Comments Off on Chemoembolization of Lung Tumors

Model Lung unilateral embolization with DSM ± carboDDP, rats: study of pulmonary microcirculation by measurement of FITC-labeled erythrocytes N 12 (2 × 6) Objective Pulmonary microcirculation Comparisons 1. unilateral embolization with DSM 2. unilateral…

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