ONCOLOGY

Triple-Negative Breast Cancer

Jun 4, 2017 by in ONCOLOGY Comments Off on Triple-Negative Breast Cancer

Fig. 29.1 This is a Venn diagram depicting the overlap patterns between TNBC, basal-like breast cancer, and BRCA-1-associated breast cancers The luminal subtypes of breast cancer express high amounts of…

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Mastectomy for Invasive Breast Cancer

Jun 4, 2017 by in ONCOLOGY Comments Off on Mastectomy for Invasive Breast Cancer

Fig. 14.1 Oblique elliptical incision for simple mastectomy An incision is made through the dermis and the skin is elevated using penetrating skin hooks. A dissection plane is developed in…

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Inflammatory Breast Cancer

Jun 4, 2017 by in ONCOLOGY Comments Off on Inflammatory Breast Cancer

Fig. 15.1 (a) Punch biopsy of the skin demonstrates small-, medium-, and large-sized lymphovascular tumor emboli and the superficial dermis from a patient with clinical manifestation of IBC. (b) The…

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Adjuvant Biologic Agents for Breast Cancer

Jun 4, 2017 by in ONCOLOGY Comments Off on Adjuvant Biologic Agents for Breast Cancer

  Number of patients DFS/RFS HR (95 %CI or p value) OS Cardiotoxicity Comments NSABP B31/N9831 [35] 5,548 0.60 (0.53–0.68) 0.63 (0.54–0.73) 4.1 % The N9831 also included a sequential…

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Adjuvant Therapy for Breast Cancer: Hormonal Therapy

Jun 4, 2017 by in ONCOLOGY Comments Off on Adjuvant Therapy for Breast Cancer: Hormonal Therapy

Toxicity HR Endometrial cancer 3.28 Pulmonary embolism 2.15 Deep venous thrombosis 1.44 Bone fractures 0.68 In the most recent Oxford Overview Analysis, there was a nonsignificant increase in stroke deaths…

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