ONCOLOGY

Rare Tumors

Sep 26, 2017 by in ONCOLOGY Comments Off on Rare Tumors

WHO grade I Benign meningiomas: with low risk of recurrence and/or low risk of aggressive growth WHO grade II Atypical meningiomas: with increased mitotic activity or three or more of…

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Late Effects of Treatment and Palliative Care

Sep 26, 2017 by in ONCOLOGY Comments Off on Late Effects of Treatment and Palliative Care

Fig. 17.1 CNS tumor all-cause and sex-specific mortality rate compared with age-adjusted US population (Armstrong et al. 2009a) (Reprinted with permission ©2009 Oxford University Press, all rights reserved) 17.2.2 Secondary…

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Intramedullary Spinal Cord Tumors

Sep 26, 2017 by in ONCOLOGY Comments Off on Intramedullary Spinal Cord Tumors

Pain Motor regression Weakness Gait abnormality/deterioration Torticollis Progressive kyphoscoliosis Hydrocephalus Sphincter disturbance Reflex changes Sensory impairment 10.2.3.1 Diagnostic Imaging MRI is the diagnostic tool of choice for all spinal tumors…

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Ependymoma

Sep 26, 2017 by in ONCOLOGY Comments Off on Ependymoma

Fig. 4.1 Myxopapillary ependymoma, WHO grade I, demonstrates centrally placed hyalinized blood vessels, surrounded by mucinous microcystic degeneration and collars of small epithelioid ependymal cells (courtesy of Dr. A. Perry)…

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Low-Grade Gliomas

Sep 26, 2017 by in ONCOLOGY Comments Off on Low-Grade Gliomas

Fig. 1.1 Histopathological features of pilocytic astrocytoma. (a) Field of tumor cells demonstrating increased cellularity, mild nuclear atypia, and lack of mitoses. (b) Tumor edge with gliotic border (left of…

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Craniopharyngioma

Sep 26, 2017 by in ONCOLOGY Comments Off on Craniopharyngioma

Fig. 7.1 Rathke’s pouch projects from the roof of the stomodeum and grows toward the infundibulum during the fourth week of gestation. During the sixth week of gestation, the connection…

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Choroid Plexus Tumors

Sep 26, 2017 by in ONCOLOGY Comments Off on Choroid Plexus Tumors

Fig. 9.1 A large choroid plexus papilloma. (a) A sagittal precontrast T1-weighted MRI demonstrates a large lobulated mass within the lateral ventricle with associated enlargement of the ventricle. (b, c)…

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Intracranial Germ Cell Tumors

Sep 26, 2017 by in ONCOLOGY Comments Off on Intracranial Germ Cell Tumors

Benign germ cell tumors Malignant germ cell tumors Immature teratomaa Germinoma Mature teratoma Embryonal carcinoma Endodermal sinus tumor (yolk sac tumor) Choriocarcinoma Mixed germ cell tumor Teratoma with malignant transformation…

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Neuronal Tumors

Sep 26, 2017 by in ONCOLOGY Comments Off on Neuronal Tumors

Fig. 8.1 Ganglioglioma. (a) T1-weighted axial MRI with gadolinium of a ganglioglioma in the left temporal lobe. Nodular enhancement is seen. (b) Hematoxylin and eosin staining reveals large, dysplastic neurons…

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Chemotherapy

Sep 26, 2017 by in ONCOLOGY Comments Off on Chemotherapy

Study Number of patients, age at transplant Pre-transplant status Conditioning Posttransplant therapies Outcome Kalifa et al. (1992) 6, age 8 months to 16 years All patients had residual disease Busulfan,…

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