Complications Following Hepatectomy
As the number of liver resections in the United States has increased, operations are more commonly performed on older patients with multiple comorbidities. The advent of effective chemotherapy and techniques…
ONCOLOGY
Systemic Therapy for Hepatocellular Carcinoma and Cholangiocarcinoma
Understanding core signaling pathways in hepatic carcinogenesis has brought about a new era in the management of hepatocellular carcinoma. Sorafenib was the first molecular targeted therapy to be approved for…
Y90 Selective Internal Radiation Therapy
Primary liver malignancies and liver metastases are affecting millions of individuals worldwide. Because of their late and advanced stage presentation, only 10% of patients can receive curative surgical treatment, including…
Transarterial Chemoembolization for Primary Liver Malignancies and Colorectal Liver Metastasis
Management of liver malignancies, both primary and metastatic, requires a host of treatment modalities when attempting to prolong survival. Although surgical resection and transplantation continue to offer the best chance…
Modern Technical Approaches in Resectional Hepatic Surgery
Techniques in liver surgery have improved considerably during the last decades, allowing for liver resections with low morbidity and mortality. Preoperative patient selection, perioperative management, and intraoperative blood-sparing techniques are…
Ablative Technologies for Hepatocellular, Cholangiocarcinoma, and Metastatic Colorectal Cancer of the Liver
A wide array of ablation technologies, in addition to the progressive sophistication of imaging technologies and percutaneous, laparoscopic, and open surgical techniques, have allowed us to expand treatment options for…
Prognostication Systems as Applied to Primary and Metastatic Hepatic Malignancies
Staging systems are an attempt to incorporate the biology and therapy for cancer in a way that enables categorization and prediction of oncologic outcomes. Because of unusual disease biology and…
Epidemiology of Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the most common histologic type of primary liver cancer, accounting for between 85% and 90% of these malignancies. The overall prognosis of patients with liver cancer…
Hepatocellular Cancer, Cholangiocarcinoma, and Metastatic Tumors of the Liver
Lawrence D. Wagman, MD, FACS, Editor Development of an issue for the Surgical Oncology Clinics of North America is initiated by defining an area of need and interest. Interest in…
Hepatocellular Cancer, Cholangiocarcinoma, and Metastatic Tumors of the Liver
Nicholas J. Petrelli, MD, FACS, Consulting Editor This issue of the Surgical Oncology Clinics of North America discusses hepatocellular cancer, cholangiocarcinoma, and metastatic tumors of the liver. The guest editor…
