Diagnostic Workup of Lung Cancer
Lung cancer is the most frequent cause of mortality worldwide. According to recent estimates, 222,520 new cases of lung cancer (non–small cell and small cell combined) were diagnosed and 157,300…
ONCOLOGY
Updated Staging System for Lung Cancer
The seventh edition of TNM for Lung Cancer came into effect on the first of January 2011. Containing more than 100,000 cases of lung cancer treated by all modalities of…
The Changing Pathology of Lung Cancer
Lung cancer classification is of paramount importance in determining the treatment for oncologic patients. Most lung cancers are non–small cell lung carcinomas (NSCLC), which are further subclassified into squamous cell…
Epidemiology of Lung Cancer: Smoking, Secondhand Smoke, and Genetics
The link between smoking and development of lung cancer has been demonstrated, not only for smokers but also for those exposed to secondhand smoke. Despite the obvious carcinogenic effects of…
Screening for Lung Cancer: Challenges for the Thoracic Surgeon
Lung cancer is a global health burden and is among the most common and deadly of all malignancies worldwide. Early detection of resectable and potentially curable disease may reduce the…
Laparoscopic Resection for Gastric Carcinoma: Western Experience
There has been much speculation regarding differences in outcome for patients who have gastric cancer in the Eastern versus Western world. Among other factors, these differences have contributed to a…
Molecular Markers for Incidence, Prognosis, and Response to Therapy
Lung cancer is the most common malignancy in the United States and worldwide. In 2011, it is estimated that more than 221,000 people in the United States will be diagnosed…
Endoscopic Mucosal Resection, Endoscopic Submucosal Dissection, and Beyond: Full-Layer Resection for Gastric Cancer with Nonexposure Technique (CLEAN-NET)
Mucosal cancer in the gastrointestinal tract generally has low risk of lymph node metastasis. Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are techniques of local excision of neoplasia…
Phase I and II Clinical Trials for Gastric Cancer
Gastric cancer remains a global public health problem with considerable heterogeneity in pathogenesis and clinical presentation across geographic regions. Improved understanding of the molecular biology of this disease has opened…
Preoperative and Postoperative Chemotherapy for Gastric Cancer
Radical surgery offers the only chance of cure for patients with operable gastric cancer; however, outcomes remain generally poor due to a high rate of relapse post gastric surgery. Multimodality…
