Fig. 5.1 Serous tubal intraepithelial carcinoma. Proliferation of epithelial cells with high-grade atypia replaces the surface of tubal fimbrial epithelium. (a) low power, (b) high power Fig. 5.2 p53 signature….

Type <20 years 20–50 years >50 years Coelomic epithelium 29% 71% 81% Germ cell 59% 14% 6% Specialized gonadal stroma 8% 5% 4% Non-specific mesenchyme 4% 10% 9% Some patients with ovarian cancer…

SEER (NCI) 15–29-year-old Adolescent and young Adult Oncology Progress Review Group 15–39-year-old NCCN 15–39-year-old 15.3 Cancer in AYAs Worldwide Including Ovarian Cancer In the United States, 70,000 AYAs are diagnosed…

Fig. 9.1 Serous borderline tumor, micropapillary pattern. Non-hierarchial pattern is shown with micropapillary projection five times longer than width at least 5 mm in dimension with fibrous stalks The prognosis…

Specificity activation Non-specific (activate systemic immunity, relatively old) Specific (target cancer cells or cancer-specific antigens, relatively old) Active immunization (to elicit immunity in vivo) Biological response modifier Cancer vaccine Dendritic…

Fig. 3.1 The major morphological types of epithelial ovarian tumors and the mimic normal epithelia; (a and b) fallopian tubal epithelium (a) and serous carcinoma (b); (c and d) endometrium…

Fig. 17.1 (a) Institutions where end-of-life care was provided [33]. (b) Waiting periods for transfer to a palliative care unit [33] Fig. 17.2 (a) Treatment modalities for managing ascites (multiple…

Fig. 10.1 Treatment of malignant sex cord-stromal tumors. *Fertility-preserving surgery—affected-side salpingo-oophorectomy + omentectomy + peritoneal cytology + detailed intra-abdominal examination. **Lymph node dissection (biopsy) can be omitted. Reprint with permission from ref. 21 10.3 Malignant Ovarian…

Fig. 16.1 Cycle of frailty [66], reprinted with permission of Oxford University Press Fig. 16.2 Hypothesized molecular and physiological association with frailty [67], reprinted with permission of John Wiley and…