Fig. 1 Schematic diagram demonstrating mode of action of new oral anticoagulants (NOAC) on the coagulation pathway Meanwhile, Factor Xa inhibitors selectively and reversibly bind directly to the active site…

Fig. 1 Mechanism of action of unfractionated heparin, low-molecular-weight heparin, and fondaparinux Only one-third of UFH molecule contain the high-affinity pentasaccharide required for anticoagulant effect [22]. The UFH fraction with…

© Springer International Publishing Switzerland 2016Md. Shahidul Islam (ed.)Thrombosis and Embolism: from Research to Clinical PracticeAdvances in Experimental Medicine and Biology90610.1007/5584_2016_102 The Use of Surgical Care Improvement Projects in Prevention of Venous Thromboembolism…

© Springer International Publishing Switzerland 2016Md. Shahidul Islam (ed.)Thrombosis and Embolism: from Research to Clinical PracticeAdvances in Experimental Medicine and Biology90610.1007/5584_2016_101 Thromboembolic Prophylaxis for Morbidly Obese Patients Undergoing Bariatric Surgery Jaime Ruiz-Tovar1   and Carolina Llavero2…

“Absolute” contraindications:  Ongoing bleeding or recent severe bleeding  Known bleeding diseases  Intracranial bleeding or previous intracranial bleeding  Structural intracranial cerebrovascular diseases that increase risk for bleeding (e.g., aneurysm)  Some malignant…

Fig. 1 Virchow’s triad (Virchow’s triad: thrombosis adviser) Table 1 Risk factors for VTE (Rashid et al. 2005) Over 60 years age Critical care admission Dehydration Known thrombophilias Obesity (body mass…

Acute onset dyspnea 80 % Gradual onset dyspnea  3 % Orthopnea  0.4 % Chest pain 49 % Syncope 24 % Hemoptysis  6 % As discussed below, although these symptoms are often due to serious disease, they…