Targeted Therapy
BACKGROUND Print Section Listen Chemotherapy has been the mainstay of systemic treatment of cancer for nearly 75 years. Chemotherapy can be broadly classified as either cytotoxic (killing rapidly dividing cells)…
ONCOLOGY
Patient Safety in Surgical Oncology
BACKGROUND Print Section Listen Harm from medical mistakes can be catastrophic to the patient, and can also damage the reputation of a surgeon and institution. Today, patients, payers, and clinicians…
Outcomes Research
INTRODUCTION Print Section Listen In 2013, an estimated 1.7 million people in the United States will be newly diagnosed with cancer.1 With advances in multidisciplinary care, there has been a…
American Board of Surgery Certificate in Complex General Surgical Oncology: Rationale and History
INTRODUCTION Print Section Listen On March 22, 2011, the American Board of Medical Specialties (ABMS) unanimously approved the application for a certificate in Complex General Surgical Oncology.1–3 Until then there…
Evolution of Surgical Oncology
INTRODUCTION Print Section Listen Whether considering the practice of bloodletting or the concept of balancing of the four humors, the practice of medicine dates back centuries to the time of…
Defining the Specialty of Surgical Oncology
INTRODUCTION Print Section Listen “…The oncologic surgeon is well trained in general surgery, and then has overlying training in special oncologic surgery. He must be knowledgeable about radiation therapy, chemotherapy…
Nutritional Support and Electrolyte Management
INTRODUCTION AND HISTORICAL PERSPECTIVE Print Section Listen Dietary choices impact disease. In the outpatient setting, dietary choices influence our risk for heart disease, cancers, obesity, diabetes, and stroke1,2; poor dietary…
Post-Injury Inflammation and Organ Dysfunction
HISTORICAL PERSPECTIVE: EVOLVING CONCEPTS ON THE PATHOGENESIS OF MULTIPLE ORGAN FAILURE Print Section Listen Our increasing ability to keep severely injured patients alive eventually created a new clinical syndrome known…
Renal Failure
INTRODUCTION Print Section Listen The average 70-kg person has 42 L of water divided into the intracellular space (ICF) of 28 L and the extracellular space (ECF) of 14 L….
Critical Appraisal of Trauma Research
INTRODUCTION Print Section Listen Good doctors use both individual clinical expertise and the best available external evidence, and neither alone is enough. Without clinical expertise, practice risks becoming tyrannized by…
