4 Innate (General or Nonspecific) Host Defense Mechanisms Carl W. Dieffenbach, Edmund C. Tramont Keywords adaptive immunity; antimicrobial proteins; C-type lectin (CLR)-like receptor family; innate immunity; natural antibodies; NOD-like receptor…
13 Epidemiologic Principles Michael T. Osterholm, Craig W. Hedberg Keywords chain of infection; experimental studies; infectivity; observational studies; odds ratio; pathogenicity; virulence; relative risk; sensitivity; specificity Epidemiologic Study Methods Epidemiology…
10 Human Genetics and Infection Stephen J. Chapman, Adrian V.S. Hill Keywords gene; genome-wide; hemoglobinopathy; HIV; human leukocyte antigen; malaria; mycobacteria; natural selection; polymorphism; Toll-like receptor Genetic variation in the…
2 The Human Microbiome of Local Body Sites and Their Unique Biology Kjersti Aagaard, Ruth Ann Luna, James Versalovic Keywords beneficial microbes; commensalism; dysbiosis; metagenome; microbial ecology; microbiome; microbiota; mutualism;…
1 A Molecular Perspective of Microbial Pathogenicity David A. Relman *, Stanley Falkow Keywords bacteriophage; clonality; commensal; commensalism; diagnostics; ecology; evolution; genomics; horizontal gene transfer; infectious diseases; intracellular parasites; metagenomics;…
Collection site Comments Abscesses, subcutaneous sites Aspirate abscess; sample base of subcutaneous lesions Blood Use maximum amount of blood recommended for the system being used Bone marrow Pediatric Isolator™ recommendedb…
Condition Presentation Differential diagnosis Tinea pedis Interdigital: scaling, fissuring, maceration, erosions, hyperhidrosis, pruritus, odor Candidiasis, erythrasma, bacterial infection, psoriasis, contact dermatitis, dyshidrotic eczema, Reiter’s syndrome Moccasin: fine silvery scales with…
Radiological finding Fungus Granulomas or solid enhancing lesions Aspergillus, Cryptococcus, Histoplasma, Candida, Paracoccidioides Abscesses Aspergillus, Blastomyces (epidural), Coccidioides, Cryptococcus, Candida, dematiaceous fungi, Pseudallescheria boydii (Scedosporium apiospermum) Parenchymal/leptomeningeal nodules; pseudocysts Cryptococcus…
Fig. 4.1 Budding cell of Blastomyces dermatitidis. Note that the daughter cell is almost as large as the mother cell and still connected by a pore. H&E hematoxylin and eosin….
Coccidioides was originally described as noted above as one species, C. immitis. More recently, two genetically distinct populations of Coccidioides have been described, C. immitis and Coccidioides posadasii, correlating to…
