Palliative Care
Antiemetic agent Action Dosage Side effects Anticholinergics/ antimuscarinics A direct depressant action on the VC. An antispasmodic action on the gut. Useful for motion sickness and post-operative N/V (PONV) Hyoscine…
HEMATOLOGY
Posttransplant Relapse
© Springer Science+Business Media, LLC 2015Richard T. Maziarz and Susan Schubach Slater (eds.)Blood and Marrow Transplant Handbook10.1007/978-3-319-13832-9_32 32. Posttransplant Relapse Marlise R. Luskin1 and David L. Porter1 (1) Division of Hematology/Oncology and the Abramson Cancer Center, Perelman…
Secondary Malignancies
Alkylating agents Topoisomerase II inhibitors Latency 3–8 years 2–3 years Incidence 2–20 % 2–12 % Myelodysplastic phase Present Absent FAB type M1, M2 M4, M5 Cytogenetics 5-, 7-, 5q-, 7q- 11q23…
Graft Failure
Type of product TNC/kg body weight of recipient CD34 + cell/kg body weight of recipient Bone marrow > 2 × 108 Peripheral blood stem cells > 2 × 108 > 3 × 106 Double cord blood—each unit > 2 × 107 …
Psychiatric Complications
Patient condition Suggested antidepressant drug of choice Depression with anxiety or agitation Paroxetine (Paxil®) Depression with lethargy and amotivation Fluoxetine (Prozac®), buproprion (Wellbutrin®), or venlafaxine (Effexor®) Preexisting cardiac disease Congestive…
Women’s Hormonal Health Issues
Composition Product name FDA-approved dosage Vaginal creams 17β-estradiol Estrace vaginal cream® Initial: 2–4 g/day for 1–2 weeks maintenance: 1 g/1–3 times/week Conjugated estrogens Premarin vaginal cream® For VVA: 0.5–2 g/day for 21 day…
Thrombotic Microangiopathies
Ruutu T, Barosi G, Benjamin RJ, Clark RE, George JN, Gratwohl A, et al. European Group for Blood and Marrow Transplantation; European LeukemiaNet. Diagnostic criteria for hematopoietic stem cell transplant-associated microangiopathy:…
Endocrine Complications in Childhood Cancer Survivors
Alkylating agents Busulfan Cisplatin Cyclophosphamide Ifosfamide Mechlorethamine Melphalan Nitrosureas BCNU (carmustine) CCNU (lomustine) Procarbazine Thiotepa Primary factors associated with late endocrine complications are as follows: 1. Radiotherapy: the involved field,…
Kidney Disease in Hematopoietic Stem Cell Transplantation
(1) Portland Veterans Administration Medical Center, Oregon Health & Science University, 3710 SW US Veterans Hospital Road, P3NEPH, 97239 Portland, OR, USA KeywordsAcute kidney injuryChronic kidney diseaseChronic kidney disease in…
Cardiovascular Complications
Fig. 23.1 Standard approaches to acute atrial fibrillation b. Rate controlling agents (all can cause hypotension and bradycardia and should be administered in a monitored setting) i. Metoprolol 5 mg…
