Treatment of Venous Thromboembolic Disease Sam Schulman Jeffrey Ginsberg James Douketis The management of venous thromboembolic disease has in some respects taken recent giant leaps forward but has in other…
Prevention of Venous Thromboembolic Disease Menno V. Huisman Sharif Pasha Patrick Mismetti Ajay Kakkar Venous thromboembolic disease frequently complicates the course of patients undergoing a variety of surgical interventions. Indeed,…
Sequelae of Venous Thromboembolic Disease: Postthrombotic Syndrome and Chronic Thromboembolic Pulmonary Hypertension Vittorio Pengo Susan R. Kahn POSTTHROMBOTIC SYNDROME The postthrombotic syndrome (PTS) is an important, underrecognized, chronic sequela of…
Venous Thrombosis in Unusual Sites Victor J. Marder Hylton V. Joffe Sam Schulman Venous thromboembolism (VTE) typically presents with lower extremity deep vein thrombosis (DVT) or pulmonary embolism (PE).1,2 Upper…
Clinical Manifestations and Diagnosis of Venous Thromboembolism Henri Bounameaux Arnaud Perrier Pulmonary embolism (PE), the source of which is predominantly located in a thrombosis of the deep veins of the…
Epidemiology and Risk Factors for Venous Thromboembolism John A. Heit Thrombosis can affect virtually any venous circulation. This chapter focuses on the epidemiology of common deep vein thrombosis (DVT) of…
Thrombophilia Genetics Joseph Emmerich Martine Aiach Pierre-Emmanuel Morange Each year, approximately 1 in 1,000 individuals in industrialized countries develops deep-vein thrombosis (DVT) of the lower extremities.1,2 Between 1% and 2%…
Overview of Venous Thromboembolism Sam Schulman Victor J. Marder Gilbert C. White II HISTORICAL BACKGROUND Thrombosis as a clinical condition was probably described almost 5,000 years ago, when the Chinese…
New Approaches for the Therapy of Bleeding Disorders, Including Gene Therapy Gilbert C. White II Harold R. Roberts Better understanding of the molecular mechanisms of blood coagulation and the structure…
Platelets, Plasma, and Specialized Coagulation Concentrate Therapies Thomas S. Kickler The biggest driving force in improving the safety of transfusion therapy in bleeding disorders has been the concern by patients…
