Acute Leukemias
Martin S. Tallman, MD, Guest Editor The acute leukemias represent a heterogeneous group of malignant hematopoietic stem cell disorders with myeloid characteristics. Remarkable insights have occurred in our understanding of…
HEMATOLOGY
Contemporary Quality of Life Issues Affecting Gynecologic C ancer Survivors
Regardless of cancer origin or age of onset, the disease and its treatment can produce short- and long-term sequelae (ie, sexual dysfunction, infertility, or lymphedema) that adversely affect quality of…
Advances in the Use of Radiation for Gynecologic Cancers
Radiation plays an integral role in the management of gynecologic cancers. The specific regimen must be carefully coordinated based on the details of a patient’s personal history and pathologic findings….
New Biologic Agents for the Treatment of Gynecologic Cancers
Improved understanding of the molecular basis of gynecologic cancers in addition to the availability of faster and less expensive technologies for genetic analysis of cancers has led to the exciting…
Current Surgical Management of Ovarian Cancer
Surgical management of ovarian cancer requires excellent judgment and mastery of a wide array of procedures. Involvement of a gynecologic oncologist improves outcomes. Staging of apparent stage I disease is important….
Current Management of Gestational Trophoblastic Neoplasia
Gestational trophoblastic neoplasms are malignant lesions that arise from placental villous and extravillous trophoblast. Four clinicopathologic conditions make up this entity: invasive mole (IM), choriocarcinoma (CCA), placental-site trophoblastic tumor (PSTT),…
Current Surgical Management of Endometrial Cancer
Despite being the most common gynecologic cancer in developed countries, there are many unanswered questions regarding optimal surgical management of endometrial cancer, including who should undergo surgical staging. There is…
Surgical Management of Cervical Carcinoma
Cervical cancer is the second most common cancer in women worldwide. In developed countries screening programs have decreased the incidence of this disease and improved the detection of early-stage disease…
Current Management of Vulvar Cancer
Vulvar cancer is surgically staged and is categorized by the pathologic evaluation of the vulvar tumor and the inguinofemoral lymph nodes. All tumors more invasive than 1 mm and larger…
Management of Cervical Precancers: A Global Perspective
The incidence and mortality of cervical cancer have decreased dramatically over the past 70 years in well-developed countries through successful screening programs using cytologic examination, followed by evaluation and treatment…
