Introduction The diagnosis of diabetic sensorimotor polyneuropathy (DSP) depends heavily on the demonstration of objective electrophysiological nerve abnormalities through nerve conduction studies (NCS) along with the assessment of clinical signs…
Introduction Our understanding of diabetes mellitus (DM) had advanced substantially by the end of the 19th century. Observations by Minkowski and von Mering around that time made a key conceptual…
Introduction Peripheral somatic and autonomic neuropathy are major risk factors predicting future mortality in diabetes . Therefore prevention and treatment of neuropathy are important not only in reducing the patient…
Introduction Diabetic foot disease (DFD) is a major global burden for patients and health care systems and is one of the most serious complications of diabetes mellitus . It encompasses…
Epidemiology and historical trials in diabetic polyneuropathy Diabetic neuropathy is the most common cause of distal symmetric polyneuropathy (DSP) worldwide . It generates the most morbidity and is linked to…
Introduction “Insulin neuritis” is a historical term for acute painful neuropathy related to the initiation of insulin treatment and the subsequent improvement in glycemic control in patients with diabetes. Caravati…
Introduction Diabetes mellitus is a major metabolic disorder. Nearly half a billion people are living with diabetes worldwide. International Diabetes Federation estimated that over four million people aged 20–79 years…
Models of care for falls and fracture prevention The authors of this chapter work at Vancouver General Hospital, a quaternary care center in British Columbia, Canada. As a major medical…
Acknowledgments The authors report no relevant disclosures or conflicts of interest. Dr. Troen is supported by grants from the National Institutes of Health (K07 AG060266), Veterans Affairs (BX004369), and the…
Introduction As the global population ages, the ongoing impact of osteosarcopenia is poised to strain or overwhelm healthcare systems around the world . To combat this, effective treatment strategies are…
