Hematopoietic Growth Factors Jeffrey Crawford Susan Blackwell Hematopoietic growth factors are glycoproteins that stimulate the proliferation and development of clonogenic precursor cell populations. Through recombinant technology, hematopoietic growth factors administered…
Clinical Trials Jeanette A. Linebaugh WHAT ARE CLINICAL TRIALS AND WHY SHOULD THEY BE DONE? New medical knowledge can be acquired and disseminated in many ways, including case reports, collected…
Principles of Chemotherapy Carl E. Freter SINGLE AGENTS The term “chemotherapy” was coined by Paul Ehrlich in the early 20th century in a search for compounds to act as “magic…
Drug Resistance Carl E. Freter James Goldie The capacity of cancer cell populations to express high orders of resistance to all of the currently available cancer therapeutic agents remains a…
Norton-Simon Hypothesis Patrick G. Morris Teresa A. Gilewski Larry Norton All modern medical science is based on pathophysiology, the study of the structure and function of normal organs and how…
Scientific Basis of Cancer Chemotherapy Michael C. Perry Carl E. Freter Until recently the majority of chemotherapeutic agents in use today were developed empirically. Knowledge of the regulation of growth…
