Cancer Survivorship
Cancer Survivorship CANCER SURVIVORSHIP Elizabeth Won Matthew J. Matasar Overview W/improvement in dx & tx of CA, there are millions of CA survivors, w/the number increasing Pts experience the nl…
Pain and Palliative Care
Pain and Palliative Care PRINCIPLES OF PALLIATIVE MEDICINE Rebecca T. Armendariz Stacy M. Stabler What is Palliative Care? Definition: Palliative medicine is a specialized medical care for people w/serious or…
Cancer Complications
Cancer Complications TUMOR LYSIS SYNDROME Jarett L. Feldman Matthew J. Matasar Definition TLS is the metabolic abnormalities a/w spontaneous &/or tx-induced cell death that can be potentially fatal in certain…
Cancer Pharmacology
Cancer Pharmacology PHARMACOGENETICS AND PHARMACOGENOMICS Mabel Rodriguez Introduction Pharmacogenetics: Effect of heritability on response to drugs. Study of single genes & their effects on interindividual differences in drug metabolizing enzymes….
Cancer Genetics
Cancer Genetics BRCA1/2 Payal D. Shah Kenneth Offit Mark Robson Biology Genes: BRCA1 on chromosome 17q, BRCA2 on 13q Function: TSGs; proteins function in double-stranded DNA damage repair by homologous…
Cancer Immunology
Cancer Immunology CANCER IMMUNOBIOLOGY Gabriela Soriano Hobbs Alexander M. Lesokhin Cancer Immunology Basics The immune system plays an important role in CA surveillance; Rx that modulate & amplify the immune…
Molecular Diagnostics
Molecular Diagnostics SEQUENCING Chung-Han Lee Classic Sanger Sequencing Developed in 1977 by Frederick Sanger & colleagues Required reagents DNA template (what you want to seq) DNA primer (known seq) dNTPs…
Cancer Biology
Cancer Biology CANCER HALLMARKS & STEM CELLS Alexander Drilon Hallmarks of Cancer CAs share a set of common distinctive & complementary capabilities that enable tumor growth & met dissemination (Cell…
Radiation Oncology
Radiation Oncology BASIC RADIATION BIOLOGY AND PHYSICS Gaorav P. Gupta Barry S. Rosenstein Definitions Ionizing Radiation (IR): Photons that have adequate energy to eject orbital electrons from target molecules X-rays:…
Clinical Research Methods
Clinical Research Methods PHASE I CLINICAL TRIALS Connie Lee Batlevi David R. Spriggs Phase 0 Trials Proof of concept trials designed to be first in human (Nat Rev Cancer 2007;7:131)…
