Prognostic Factors in Patients with Head and Neck Cancer Sung Kim Benjamin D. Smith Bruce G. Haffty INTRODUCTION Treatment of head and neck cancer requires accurate risk stratification in order…
General Principles of Head and Neck Pathology Bruce M. Wenig Jean-Marc Cohen The surgical pathologist is an integral member of the clinical team that administers to the head and neck…
Clinical Evaluation of the Head and Neck Cancer Patient Joshua D. Hornig Barry T. Malin Brendan O’Connell GENERAL APPROACH TO THE HEAD AND NECK CANCER PATIENT Clinical evaluation of the…
Benign Hematology BIOLOGY OF HEMATOPOIESIS Anita Kumar Definition of Hematopoiesis: The formation of blood cells Sites of Hematopoiesis Bone marrow (BM) is the principal site of hematopoiesis in adults, predominantly…
Stem Cell Transplantation AUTOLOGOUS STEM CELL TRANSPLANTATION Amanda L. Olson Craig Sauter Description HDC/radiation followed by infusion of autologous multipotent hematopoietic stem cells. Tx of hematologic malignancies using HDC/radiation followed…
Leukemias and Myelodysplastic Syndromes MYELODYSPLASTIC SYNDROMES Justin M. Watts Virginia M. Klimek Epidemiology ˜10000 cases diagnosed annually in the United States Incidence >20/100000 in adults >70 y → actual incidence…
Myeloproliferative Disorders ESSENTIAL THROMBOCYTHEMIA Raajit Rampal Clonal hematopoietic disorder resulting in ↑ red cell mass Epidemiology Incidence: Median age at dx is 60 y. 1/5 of pts under age 40…
Plasma Cell Disorders MGUS AND MULTIPLE MYELOMA (MM) Patrick W. Burke Hani Hassoun Definition Monoclonal gammopathy of undetermined significance (MGUS): Premalignancy w/clonal plasma cell (PC) proliferation. No e/o other B-cell…
Cancer of Unknown Primary CANCER OF UNKNOWN PRIMARY (CUP) Jean K. Lee Lewis J. Kampel Overview & Epidemiology CUP, or occult 1° tumors: Histologically proven malignant tumors w/o an identified…
