Metastatic Epidural Spinal Cord Compression Soma Sengupta Michael W. Groff Nils D. Arvold Patrick Y. Wen INTRODUCTION Epidural spinal cord compression (ESCC), resulting from tumor growth in the spinal epidural…
Brain Metastases Nancy U. Lin Brian M. Alexander Ian F. Dunn The management of patients with brain metastases from breast cancer remains a challenging clinical problem. The goals of treatment…
Newer Targeted Therapy Ingrid A. Mayer Carlos L. Arteaga Advances in tumor genetics and drug development over the last decade have led to the generation of a wealth of anti-cancer…
Management Summary for the Care of Patients with Metastatic Breast Cancer Marc E. Lippman Very unfortunately, metastatic breast cancer remains largely incurable. Therefore, the primary goals of therapy are the…
Palliative Care in Breast Cancer M. Jennifer Cheng Thomas J. Smith INTRODUCTION Breast cancer is still the most common cancer in women and nearly half of those diagnosed will die…
Treatment of HER2-overexpressing Metastatic Breast Cancer Shruti Sheth Sumanta Kumar Pal Mark D. Pegram INTRODUCTION In 2013, it is estimated that 232,340 new cases of breast cancer will be diagnosed…
Treatment of Metastatic Breast Cancer: Chemotherapy Sing-Huang Tan Antonio C. Wolff INTRODUCTION In 2013, the United States had an estimated 232,340 new cases of breast cancer and 39,620 breast cancer-related…
Treatment of Metastatic Breast Cancer: Endocrine Stephen R.D. Johnston Gaia Schiavon INTRODUCTION The optimal management of patients with metastatic breast cancer (MBC) remains a challenge. Systemic drug treatments such as…
Management of Local Regional Recurrences after Primary Breast Cancer Treatment Meena S. Moran Anees B. Chagpar Erica L. Mayer INTRODUCTION Contemporary treatments for early-stage breast cancer have minimized the risk…
Surgery for the Primary in Patients with Distant Metastases Tari A. King The traditional dogma that surgery is reserved for the palliation of symptoms in stage IV breast cancer is…
