USE OF BIOCHEMICAL MARKERS OF BONE TURNOVER IN OSTEOPOROSIS
USE OF BIOCHEMICAL MARKERS OF BONE TURNOVER IN OSTEOPOROSIS Part of “CHAPTER 56 – MARKERS OF BONE METABOLISM“ Since the previous edition of this textbook, major advances have been made…
MARKERS OF BONE METABOLISM
MARKERS OF BONE METABOLISM Part of “CHAPTER 56 – MARKERS OF BONE METABOLISM“ Assays of biochemical markers of bone turnover are noninvasive and, when the results are applied and interpreted…
BIOCHEMISTRY OF BONE
BIOCHEMISTRY OF BONE Part of “CHAPTER 56 – MARKERS OF BONE METABOLISM“ Bone is composed of ˜70% mineral and 30% organic matter. The mineral, primarily in the form of hydroxyapatite…
MARKERS OF BONE METABOLISM
MARKERS OF BONE METABOLISM Markus J. Seibel Simon P. Robins John P. Bilezikian Bone is a metabolically active tissue that throughout life undergoes constant remodeling. Skeletal turnover is achieved by…
VARIABLES ROUTINELY MEASURED IN THE ANALYSIS OF THE BIOPSY SPECIMEN
VARIABLES ROUTINELY MEASURED IN THE ANALYSIS OF THE BIOPSY SPECIMEN Part of “CHAPTER 55 – BONE QUANTIFICATION AND DYNAMICS OF TURNOVER“ An abundance of quantitative information may be obtained from…
TECHNIQUE OF ILIAC CREST BIOPSY
TECHNIQUE OF ILIAC CREST BIOPSY Part of “CHAPTER 55 – BONE QUANTIFICATION AND DYNAMICS OF TURNOVER“ PRETREATMENT OF THE PATIENT WITH TETRACYCLINE The information obtainable from an iliac crest biopsy…
BONE QUANTIFICATION AND DYNAMICS OF TURNOVER
BONE QUANTIFICATION AND DYNAMICS OF TURNOVER David W. Dempster Elizabeth Shane The period since the 1970s has produced tremendous growth in the understanding of the pathophysiology of bone. This has…
ASSESSMENT OF VITAMIN D STATUS
ASSESSMENT OF VITAMIN D STATUS Part of “CHAPTER 54 – VITAMIN D“ Because of the wide anatomic distribution of the sites of synthesis, metabolism, and action of vitamin D, clinical…
MEASUREMENT OF VITAMIN D METABOLITES
MEASUREMENT OF VITAMIN D METABOLITES Part of “CHAPTER 54 – VITAMIN D“ METHODS The measurement of vitamin D in biologic fluids was pioneered with bioassays that measured either the linear…
BIOLOGIC ACTIONS OF VITAMIN D
BIOLOGIC ACTIONS OF VITAMIN D Part of “CHAPTER 54 – VITAMIN D“ INTESTINE CALCIUM TRANSPORT The most important bioeffect of 1,25(OH)2D3 is to increase the intestinal absorption of calcium. Although…
