IDIOPATHIC JUVENILE OSTEOPOROSIS Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Idiopathic juvenile osteoporosis is a poorly characterized, heterogeneous condition that almost certainly has a variety…
METAPHYSEAL AND SPONDYLOMETAPHYSEAL DYSPLASIAS Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Not all disorders in children that result in widened growth plates and metaphyseal irregularity…
FIBROGENESIS IMPERFECTA OSSIUM Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Fibrogenesis imperfecta ossium is a sporadic, idiopathic disorder in which pathologic changes seem to affect…
AXIAL OSTEOMALACIA Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Axial osteomalacia features defective bone mineralization despite normal serum levels of calcium and phosphate and increased…
HYPOPHOSPHATASIA Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Hypophosphatasia is an inborn error of metabolism characterized clinically by premature tooth loss and rickets or osteomalacia,…
OSTEOGENESIS IMPERFECTA Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Osteogenesis imperfecta (OI; brittle-bone disease) is characterized by osteopenia with recurrent fractures and deformity, dental disease,…
FIBROUS DYSPLASIA Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Fibrous dysplasia, a sporadic unifocal or multifocal developmental skeletal disorder, affects either sex and often causes…
FIBRODYSPLASIA (MYOSITIS) OSSIFICANS PROGRESSIVA Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Fibrodysplasia (myositis) ossificans progressiva (FOP) features accumulation of true bone in the fibrous connective…
MIXED SCLEROSING BONE DYSTROPHY Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Related posts: DEFINITIONS THYROID-HORMONE RECEPTOR BINDING TO THYROID HORMONE RESPONSE ELEMENTS DISEASE-SPECIFIC VARIATION RADIATION…
MELORHEOSTOSIS Part of “CHAPTER 66 – RARE DISORDERS OF SKELETAL FORMATION AND HOMEOSTASIS“ Melorheostosis, a sporadic, asymmetric hyperostosis that usually affects the long bones, can cause pain and intermittent swelling…
