CONTRASEXUAL PRECOCIOUS PUBERTY Part of “CHAPTER 92 – PRECOCIOUS AND DELAYED PUBERTY“ Contrasexual precocious puberty includes excessive virilization in girls and feminization in boys. Virilization in girls is primarily due…
GONADOTROPIN-INDEPENDENT LEADING TO GONADOTROPIN-DEPENDENT PRECOCIOUS PUBERTY Part of “CHAPTER 92 – PRECOCIOUS AND DELAYED PUBERTY“ Prolonged exposure to estrogens or androgens from a peripheral source may lead to early initiation…
GONADOTROPIN-INDEPENDENT PRECOCIOUS PUBERTY Part of “CHAPTER 92 – PRECOCIOUS AND DELAYED PUBERTY“ PP may also be caused by sex steroid hormone production independent of gonadotropin stimulation (Table 92-2). McCune-Albright syndrome…
GONADOTROPIN-DEPENDENT/CENTRAL PRECOCIOUS PUBERTY Part of “CHAPTER 92 – PRECOCIOUS AND DELAYED PUBERTY“ Gonadotropin-dependent PP (Table 92-1) results from premature activation of the hypothalamic–pituitary–gonadal axis. Girls may present with breast development…
PRECOCIOUS PUBERTY Part of “CHAPTER 92 – PRECOCIOUS AND DELAYED PUBERTY“ The diagnosis of precocious puberty (PP) depends on a precise definition of the timing of normal puberty. It was…
PRECOCIOUS AND DELAYED PUBERTY Emily C. Walvoord Steven G. Waguespack Ora Hirsch Pescovitz The human reproductive system begins to mature in fetal life and is remarkably active during the first…
MALE PUBERTY Part of “CHAPTER 91 – PHYSIOLOGY OF PUBERTY“ PATTERN OF ONSET AND PROGRESSION The initial physical evidence of puberty among boys is testicular growth (see Fig. 91-1B). Because…
FEMALE PUBERTY Part of “CHAPTER 91 – PHYSIOLOGY OF PUBERTY“ PATTERN OF ONSET The mean developmental pattern of female puberty is outlined in Table 91-2 and Figure 91-1A, with the…
HYPOTHALAMIC–PITUITARY–GONADAL DEVELOPMENT Part of “CHAPTER 91 – PHYSIOLOGY OF PUBERTY“ FETAL PERIOD GnRH is present in the hypothalamus and LH and FSH are present in the pituitary, and responsive to…
DEFINITION OF PUBERTY Part of “CHAPTER 91 – PHYSIOLOGY OF PUBERTY“ Puberty is the period of life from the first signs of sexual maturation until the final attainment of physical,…
