Immunology of Human Immunodeficiency Virus Infection
Immunology of Human Immunodeficiency Virus Infection Douglas S. Kwon Bruce D. Walker INTRODUCTION In June 1981, the U.S. Centers for Disease Control and Prevention (CDC) reported five cases of Pneumocystis…
Immunity to Extracellular Bacteria
Immunity to Extracellular Bacteria Moon H. Nahm Jannet Katz INTRODUCTION Human interactions with bacteria are complex, with a consortial relationship having been developed between humans and microbes. Each human being…
Immunity to Intracellular Bacteria
Immunity to Intracellular Bacteria Anca Dorhoi Stephen T. Reece Stefan H. E. Kaufmann INTRODUCTION This chapter focuses on infections by intracellular bacteria with emphasis on both pathogenicity and general immune…
Immunity to Viruses
Immunity to Viruses Hildegund C.J. Ertl INTRODUCTION Veni, vidi, vici—I came, I saw, I conquered. If viruses could talk or see, this would be their hendiatris. Although viruses are minute…
The Immune Response to Parasites
The Immune Response to Parasites Thomas A. Wynn David L. Sacks Alan Sher Eleanor M. Riley PARASITES AND THE IMMUNE SYSTEM Distinct Features and Global Health Importance of Parasitic Pathogens…
Cell-Mediated Cytotoxicity
Cell-Mediated Cytotoxicity Judy Lieberman INTRODUCTION The most effective way the immune system can control the threats of intracellular infection and cellular transformation is by destroying infected and cancerous cells.1,2,3,4,5,6,7 When…
Complement
Complement B. Paul Morgan DEFINITIONS AND HISTORY Complement comprises a set of proteins present in plasma and other biological fluids, and on cell membranes, that together play key homeostatic roles…
Neurophysiologic Reflex Mechanisms in Immunology
Neurophysiologic Reflex Mechanisms in Immunology Sangeeta S. Chavan Kevin J. Tracey INTRODUCTION A fundamental principle in biology is that organ function is maintained within a narrow physiologic range, one optimal…
The Mucosal Immune System
The Mucosal Immune System Yasmine Belkaid INTRODUCTION Most antigens encountered by the immune system enter the body through the mucosal surfaces of the respiratory, gastrointestinal (GI), and urogenital tracts, and…
