PATHOPHYSIOLOGY
PATHOPHYSIOLOGY Part of “CHAPTER 99 – PREMENSTRUAL SYNDROME“ The pathophysiology of PMS is unknown. There appear to be two primary determinants. The first is cyclic function of the hypothalamic–pituitary–ovarian axis,…
CLINICAL MANIFESTATIONS
CLINICAL MANIFESTATIONS Part of “CHAPTER 99 – PREMENSTRUAL SYNDROME“ The symptoms of PMS fall into one of four temporal patterns (Fig. 99-1).5 The most severely affected women report having only…
DEFINITION
DEFINITION Part of “CHAPTER 99 – PREMENSTRUAL SYNDROME“ Premenstrual syndrome is the cyclic recurrence in the luteal phase of the menstrual cycle of a combination of distressing physical, psychological, and/or…
PREMENSTRUAL SYNDROME
PREMENSTRUAL SYNDROME Robert L. Reid Ruth C. Fretts Most minor physical and psychological changes that mark the endocrine cyclicity of women of reproductive age (called premenstrual molimina) are normal phenomena…
INFERTILITY AND ENDOMETRIOSIS
INFERTILITY AND ENDOMETRIOSIS Part of “CHAPTER 98 – ENDOMETRIOSIS“ The most common medical problem caused by endometriosis is pelvic pain. The second most common problem caused by endometriosis is a…
TREATMENT OF ENDOMETRIOSIS BY INCREASING ESTROGEN AND PROGESTIN ACTION
TREATMENT OF ENDOMETRIOSIS BY INCREASING ESTROGEN AND PROGESTIN ACTION Part of “CHAPTER 98 – ENDOMETRIOSIS“ The combination estrogen-progestin birth control pill, when used in a continuous (pseudopregnancy) fashion, was found…
TREATMENT OF ENDOMETRIOSIS BY INCREASING PROGESTIN ACTION
TREATMENT OF ENDOMETRIOSIS BY INCREASING PROGESTIN ACTION Part of “CHAPTER 98 – ENDOMETRIOSIS“ Many synthetic progestins are effective in the treatment of pelvic pain caused by endometriosis. High-dose progestin treatment…
TREATMENT OF ENDOMETRIOSIS: ANDROGEN THERAPY
TREATMENT OF ENDOMETRIOSIS: ANDROGEN THERAPY Part of “CHAPTER 98 – ENDOMETRIOSIS“ The first hormonal treatment of endometriosis was the intramuscular administration of testosterone. High-dose parenteral testosterone therapy was demonstrated to…
TREATMENT OF ENDOMETRIOSIS BY SUPPRESSING ESTROGEN PRODUCTION AND ACTION
TREATMENT OF ENDOMETRIOSIS BY SUPPRESSING ESTROGEN PRODUCTION AND ACTION Part of “CHAPTER 98 – ENDOMETRIOSIS“ Suppression of ovarian estrogen production is the most reliable method for causing the regression of…
ENDOMETRIOSIS LESIONS ARE STEROID RESPONSIVE
ENDOMETRIOSIS LESIONS ARE STEROID RESPONSIVE Part of “CHAPTER 98 – ENDOMETRIOSIS“ Mechanical (retrograde menstruation) and endocrine factors (estradiol, progesterone) contribute to the development of endometriosis lesions. In most women, the…
