PRIMARY HYPOGONADISM
PRIMARY HYPOGONADISM Part of “CHAPTER 115 – MALE HYPOGONADISM“ Including infertile men, primary testicular failure affects 5% to 10% of the male population.4 Although male infertility is commonly considered a…
CLINICAL CHARACTERISTICS OF HYPOGONADISM
CLINICAL CHARACTERISTICS OF HYPOGONADISM Part of “CHAPTER 115 – MALE HYPOGONADISM“ The clinical presentation of hypogonadism depends on whether the onset was in utero, prepubertal, or postpubertal. If hypogonadism is…
MALE HYPOGONADISM
MALE HYPOGONADISM Stephen R. Plymate Male hypogonadism may be defined as a failure of the testes to produce testosterone, spermatozoa, or both (Table 115-1). This may be caused by a…
FUNCTIONAL TESTS
FUNCTIONAL TESTS Part of “CHAPTER 114 – EVALUATION OF TESTICULAR FUNCTION“ Response to Human Chorionic Gonadotropin. Stimulation of testosterone secretion by hCG is a useful diagnostic test for examining Leydig…
LABORATORY EVALUATION
LABORATORY EVALUATION Part of “CHAPTER 114 – EVALUATION OF TESTICULAR FUNCTION“ TESTOSTERONE Physiologic Aspects of Testosterone Testing. Testosterone is both a paracrine regulator of spermatogenesis (see Chap. 113) and a…
CLINICAL EVALUATION
CLINICAL EVALUATION Part of “CHAPTER 114 – EVALUATION OF TESTICULAR FUNCTION“ Patients with impaired testicular function present variably, depending on the age at onset of their disease. Hypogonadism in the…
EVALUATION OF TESTICULAR FUNCTION
EVALUATION OF TESTICULAR FUNCTION Stephen J. Winters Male hypogonadism signifies impaired production of testosterone by Leydig cells, or deficient spermatogenesis, but in most clinical disorders both compartments of the testis…
IMMUNOLOGIC CONTROL IN THE TESTIS
IMMUNOLOGIC CONTROL IN THE TESTIS Part of “CHAPTER 113 – MORPHOLOGY AND PHYSIOLOGY OF THE TESTIS“ There is increasing interest in the concept that the testis is an immunologically privileged…
SPERMATOGENESIS
SPERMATOGENESIS Part of “CHAPTER 113 – MORPHOLOGY AND PHYSIOLOGY OF THE TESTIS“ The sequence of cytologic changes that produce spermatozoa from spermatogonia is called spermatogenesis. It can be subdivided into…
INTERCOMPARTMENTAL MODULATION IN THE TESTIS
INTERCOMPARTMENTAL MODULATION IN THE TESTIS Part of “CHAPTER 113 – MORPHOLOGY AND PHYSIOLOGY OF THE TESTIS“ Throughout this chapter, the seminiferous tubules and intertubular tissue have been considered as independent…
