Translational Cancer Research for Surgeons
William G. Cance, MD, Editor Over the last 20 years, we have gained a massive amount of knowledge about the genetic basis of human cancer. Culminating with the sequencing of…
An Approach to the Newly Diagnosed Colorectal Cancer Patient with Synchronous Stage 4 Disease
At initial presentation, 20% to 30% of patients with colon and rectal cancer have detectable metastatic disease. Precise guidelines are lacking for the treatment of this special subset. Most of…
Functional Consequences of Colorectal Cancer Management
Functional outcomes of colorectal cancer treatment are an increasingly prominent interest of patients, clinicians, and researchers. The current literature on function after colorectal cancer treatment is difficult to assimilate, with…
Management of Complete Response After Chemoradiation in Rectal Cancer
There are an increasing number of reports on nonoperative management of rectal cancer patients who achieve a dramatic response to neoadjuvant therapy. This review discusses the current literature, and describes…
Controversies in Abdominoperineal Excision
Abdominoperineal excision (APE) is a necessary operation in many patients with low rectal cancer. Outcomes after this procedure, however, have been variable and often suboptimal. With a new concept of…
Current Controversies in Neoadjuvant Chemoradiation of Rectal Cancer
Total mesorectal excision with preoperative radiation and chemotherapy provide the lowest local recurrence rates for rectal cancer. Timing of surgery after preoperative chemoradiation is being increased to optimize tumor downstaging….
Imaging in Rectal Cancer
Over the past several decades there have been tremendous improvements in the outcomes of patients with rectal cancer. Imaging modalities such as endorectal ultrasonography (ERUS), magnetic resonance imaging (MRI), and…
Current Practices and Challenges of Adjuvant Chemotherapy in Patients with Colorectal Cancer
Colorectal cancer is one of the most commonly diagnosed cancers in men and women in the developed world. Although surgery is the foundation of curative treatment, adjuvant chemotherapy also improves…
Controversies in Laparoscopy for Colon and Rectal Cancer
There is sufficient level I evidence to support and even recommend laparoscopy as the surgical modality of choice for colon cancer resection. Laparoscopy offers improved short-term outcomes and at least…
Colon Resection
The traditional approach to surgical resection of colonic cancer involves removal of the primary tumor together with the associated lymphovascular pedicle. In an attempt to improve oncological outcomes, several groups…
