INTRODUCTION Polycythemia, also referred to as erythrocytosis, is characterized by an increased red cell mass. There is no consensus on terminology (ie, primary familial polycythemia but postrenal transplantation erythrocytosis). Polycythemias…
DEFINITION Acquired erythrocyte fragmentation occurs when red cells are forced at high shear stress through partial vascular occlusions or over abnormal vascular surfaces. In circumstances in which fragmentation of red…
ETIOLOGY AND PATHOGENESIS Three mechanisms of drug-related immunologic injury to red cells are defined: — Hapten/drug adsorption involving drug-dependent antibodies — Ternary complex formation involving drug-dependent antibodies — Induction of…
INTRODUCTION Hemolysis represents a prominent part of the overall clinical picture in many infections. Table 21–1 lists the microorganisms associated with the induction of hemolytic anemia. TABLE 21–1ORGANISMS THAT CAUSE…
THE SPLEEN The white pulp (lymphoid tissue) functions in antigen processing and antibody production. The red pulp (monocyte-macrophage system) serves as a filter, retaining defective blood cells and foreign particles….
INTRODUCTION Print Section Listen Epidemiology Cancer of the head and neck is still a significant problem worldwide. Head and neck tumors are strongly associated with a history of smoking and…
BACKGROUND Print Section Listen Skin-sparing mastectomy (SSM) has emerged as an oncologically safe approach to early-stage breast cancer and prophylactic mastectomies.1,2 This technique improves aesthetic outcomes by preserving the maximum…
BACKGROUND Print Section Listen The grafting of skin originated among the tile-maker caste in India approximately 3000 years ago.1 In 1804, an Italian surgeon, Baronio, successfully performed a full-thickness skin…
BACKGROUND Print Section Listen Introduction Humans lose the regenerative potential for wound repair early in embryonic life and following that wounds heal by scarring. Although scarring is a protective mechanism that…
INTRODUCTION Print Section Listen Several studies have demonstrated a dramatic increase in the number of skin cancer diagnoses in recent years.1,2 These increasing numbers amount to a growing patient population…
