Oncohema Key

Keywords Sodium iodide symporter (NIS), viral vector, lentivirus, radioiodide, tumor-specific targeting promoter   Sodium Iodide Symporter Thyroid hormone synthesis requires a variety of molecules in thyroid follicular cells, including sodium…

Keywords Gene therapy, hematopoiesis, cytidine deaminase, doxycycline, miRNA, Ara-C   Background Transfer of Drug-Resistance Genes into Hematopoietic Stem Cells Given their ability to self-renewal, proliferate extensively, and differentiate into all…

Keywords Salmonella , genetic engineering, gene delivery, gene therapy, attenuation, toxicity, imaging   Introduction Gene therapy is considered to be one of the most promising therapeutic approaches for treating cancer,…

Keywords IL-12, adenovirus, RheoSwitch®, activator ligand, dendritic cells, controlled expression, intratumoral, immunotherapy   Introduction Tumors grow aggressively, are invasive, and may spread to distant metastatic sites, not only because of…

Keywords Gene therapy, drug resistance, glioblastoma, chemoprotection, in vivo selection, MGMT, hematopoietic stem cell, temozolomide   Introduction Gene therapy was initially developed as an ideal treatment for defective single-gene diseases…

Keywords Cancer gene therapy, molecular imaging, systemic gene delivery, tumor targeting, vascular targeting, bacteriophage, adeno-associated virus   Introduction Gene therapy has attracted considerable attention in the past few decades. One…

Keywords Oncolytic virus, molecular imaging, bioluminescence imaging, fluorescence imaging, PET, SPECT   Preclinical Imaging of Viral Gene Expression One important reason for the ongoing and increasing success of oncolytic viruses…