Oncohema Key

Fig. 1 Histological characteristics of CP subtypes HE stained section of ACP shows wet keratin (hash symbol), the palisaded cells (asterisk) circumscribing the tumour and the reticulo stellate cells (tilde…

Fig. 1 Computed tomography scan with calcification in the suprasellar region indicative of craniopharyngioma MRI is the diagnostic imaging of choice. It is useful to confirm the presence of cystic…

Fig. 1 Weight development in childhood-onset adamantinomatgous craniopharyngioma patients recruited in HIT Endo according to hypothalamic involvement. Body mass index (BMI) SDS is shown at time of diagnosis and at…

Fig. 1 Cartoon outlining key steps during mouse pituitary development. Rathke’s pouch (RP) forms at 9.5 dpc (days post coitum) as a thickening of the oral ectoderm (OE) at the…

Fig. 1 Ommaya catheter insertion demonstrated in an infant with the access point protruding from the scalp (a). T2-axial MRI brain scan of an unrelated craniopharyngioma patient demonstrating catheter tip…

Fig. 1 Histological specimens of adamantinomatous craniopharyngioma demonstrating epithelial regions admixed with microcysts and a reactive glial surround: (a) Haematoxylin and eosin stain; (b) Immunohistochemistry for β-catenin demonstrates nuclear and…

Cox regression models No age stratification With age stratification HR 95% CI P HR 95% CI P All patients (n = 60) Recurrence (time dependent; yes vs. no) 2.7 (1.0–7.3)…

Fig. 1 Staged therapy in a 10 year-old boy presenting with a large cystic craniopharyngioma (A). He underwent transsphenoidal decompression, with improvement in vision. The residual craniopharyngioma was evident on…

First-line Second-line (if first-line abnormal) Clinical assessment Height  Weight  Sitting height  Body mass index (BMI)  Tanner pubertal stage  Bone age  Endocrine biochemistry IGF-1/IGF-BP3 GH provocation test (e.g. insulin tolerance test,…