Type of device and regulatory classification Novel technology/relevant previous experience Clinical applications and indications Nature of exposure to the products – surface contact, implantation, ingestion Risks inherent in the use…
Fig. 3.1 Active insulin treatment with high insulin doses at diagnosis was associated to higher C-peptide in T1D children (Ludvigsson Thesis 1976) Fig. 3.2 Patients with active insulin treatment which…
© Springer International Publishing Switzerland 2017Andrea Scaramuzza, Carine de Beaufort and Ragnar Hanas (eds.)Research into Childhood-Onset Diabetes10.1007/978-3-319-40242-0_11 11. Risky Behaviours in Teens with Type 1 Diabetes: New Ideas for Research Regarding a Not Too Studied Topic…
Genes related to the lipid homeostasis Fabs The polymorphisms have been studied in several metabolic phenotypes like obesity, metabolic syndrome, hypertriglyceridemia, and insulin sensitivity [6] ELOVL6 Related with insulin resistance…
Fig. 8.1 The healthy plate teaches to organise daily food in a balanced and varied diet. The healthy plate may be organised according to age, sex, level of physical activity…
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© Springer International Publishing Switzerland 2017Andrea Scaramuzza, Carine de Beaufort and Ragnar Hanas (eds.)Research into Childhood-Onset Diabetes10.1007/978-3-319-40242-0_4 4. Adolescent Prevention of Complications M. Loredana Marcovecchio1 and David B. Dunger2 (1) Department of Paediatrics, University of Cambridge, Cambridge, UK (2) Department…
A. Randomized, controlled trials including: Multicenter trial Meta-analysis incorporating quality ratings Compelling nonexperimental evidence (i.e., “insulin to treat diabetes”) B. Well-conducted cohort studies including: Prospective cohort studies or registry Meta-analysis…
Findings observable on dilated ophthalmoscopy No retinopathy Mild nonproliferative diabetic retinopathy (NPDR) Microaneurysms only Moderate NPDR More than just microaneurysms but less than severe nonproliferative diabetic retinopathy Severe NPDR…
Stimulate and perform innovative scientific research in children and adolescents with diabetes Enhance the impact of scientific research by multicenter collaboration Share and compare data from international centers of excellence…
