Molecular Profiling of Breast Cancer and DCIS

Dec 25, 2017 by in ONCOLOGY Comments Off on Molecular Profiling of Breast Cancer and DCIS

Fig. 9.1 The increasing complexity of clinical decision-making in early-stage breast cancer 9.2 Multigene Assays in Invasive Breast Cancer: Prognostication Since 2004, several MGAs have become available to clinicians treating early-stage…

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Screening for High-Familial-Risk Women

Dec 25, 2017 by in ONCOLOGY Comments Off on Screening for High-Familial-Risk Women

Fig. 6.1 Mammography in a 52-year-old woman with three sisters diagnosed with breast cancer at ages 45, 49 and 55 years old. Digital mammography was performed annually for the past 5 years. Within…

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Guided Radiotherapy

Dec 25, 2017 by in ONCOLOGY Comments Off on Guided Radiotherapy

Fig. 1 a CT scan of the brain. b MR scan of the brain. There are two small metastatic lesions clearly visible in the MR scan that are invisible in the…

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and Image Guided Systemic Radiotherapy

Dec 25, 2017 by in ONCOLOGY Comments Off on and Image Guided Systemic Radiotherapy

Fig. 1 Select examples of radiation dose-toxicity curves demonstrating that a reduction in dose to normal organs is associated with a decrease in late organ toxicities such as pneumonitis, nephritis and…

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Modeling in Radiation Oncology

Dec 25, 2017 by in ONCOLOGY Comments Off on Modeling in Radiation Oncology

where α (1/Gy) and β (1/Gy2) are parameters that determine the shape of the curve. Indeed, a vast literature exists on the mechanistic and empirical history of this famous equation,…

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Stem Cells and Tumor Microenvironment in Radiotherapy

Dec 25, 2017 by in ONCOLOGY Comments Off on Stem Cells and Tumor Microenvironment in Radiotherapy

Fig. 1 Representative images showing the different acini structures generated from immortalized normal human breast epithelial MCF10A, breast cancer MCF7 and BCSCs isolated from MCF7 population that survived a course of…

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and Hypofractionation for Primary Tumors

Dec 25, 2017 by in ONCOLOGY Comments Off on and Hypofractionation for Primary Tumors

Fig. 1 External compression was one of the first techniques used to address tumor motion in lung SBRT Fig. 2 Image guidance with CBCT prior to delivery was sufficient to provide treatment…

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