Prognostic Markers and Models in Acute Lymphoblastic Leukemia Dieter Hoelzer University Hospital, Frankfurt am Main, Germany Acute lymphoblastic leukemia (ALL) is not a uniform disease but is characterized by subgroups…
Follicular Lymphoma Myron S. Czuczman Roswell Park Cancer Institute, Buffalo, NY, USA Case study 39.1 A 75-year-old retired schoolteacher notes an increase in some nontender bilateral neck lymph nodes (LNs)…
Diffuse Large B-Cell Lymphoma Andrew D. Zelenetz Memorial Sloan Kettering Cancer Center, and Weill-Cornell Medical Center, New York, NY, USA Introduction Diffuse large B-cell lymphoma (DLBCL) is the most common…
Eosinophilic Myeloproliferative Disorders Jason Gotlib Stanford University School of Medicine/Stanford Cancer Institute, Stanford, CA, USA Case study 27.1 A 54-year-old man with no significant medical history reports a 3-month history…
Hematopoietic Cell Transplantation in Chronic Lymphocytic Leukemia Michael R. Bishop The University of Chicago, Chicago, IL, USA Case study 32.1 A 56-year-old male presented for his annual physical examination. Over…
Chronic Myeloid Leukemia: Chronic Phase Jerald P. Radich Fred Hutchinson Cancer Research Center, Seattle, WA, USA Introduction Tyrosine kinase inhibitors (TKIs) have irrevocably changed the care of chronic myeloid leukemia…
Hematopoietic Cell Transplantation in Primary Myelofibrosis Irum Khan and Damiano Rondelli University of Illinois Hospital & Health Sciences System, Chicago, IL, USA 1. Is there a cure for myelofibrosis? Allogeneic hematopoietic…
Management of B-Cell Acute Lymphoblastic Leukemia Hady Ghanem, Hagop Kantarjian, Nitin Jain, and Elias Jabbour The University of Texas MD Anderson Cancer Center, Houston, TX, USA 1. What is the standard…
Chronic Myelomonocytic Leukemia Mrinal M. Patnaik Mayo Clinic, Rochester, MN, USA Case study 28.1 A 55-year-old male presented with a one-year history of progressive effort intolerance, 10-pound weight loss, early…
Essential Thrombocytosis Paola Guglielmelli and Alessandro M. Vannucchi The University of Florence, Florence, Italy Case study 25.1 A 35-year-old, otherwise healthy woman presents with thrombocytosis, ranging from 495 × 109/L to 600 × 109/L,…
