Fat cell steroid production Insulin secretion Androgen synthesis by the ovaries Sex hormone binding globulin production by the liver Gonadal axis is closely linked to the nutritional status. Critical percentage…
Need for intensive luteal support after GnRH triggering Rec-LH is expensive Local side effects of IM P Efficacy of vaginal P Patient compliance to SC P Proven efficiency of oral…
Menorrhagia Endometriosis Metrorrhagia Ovarian cysts Hypermenorrhea Benign breast diseases Myomas Endometrial carcinoma Adenomyosis Ovarian carcinoma Endometrial hyperplasia In such a hormonal milieu, typical menopausal symptoms and signs occur: hot flushes,…
© International Society of Gynecological Endocrinology 2016Andrea R. Genazzani and Basil C. Tarlatzis (eds.)Frontiers in Gynecological EndocrinologyISGE Series10.1007/978-3-319-23865-4_11 11. Neuroendocrine Basis of the Hypothalamus–Pituitary–Ovary Axis Aging Andrea Giannini1, Andrea R. Genazzani1 and Tommaso Simoncini1 (1) Division of Obstetrics and…
© International Society of Gynecological Endocrinology 2016Andrea R. Genazzani and Basil C. Tarlatzis (eds.)Frontiers in Gynecological EndocrinologyISGE Series10.1007/978-3-319-23865-4_5 5. Gene Expression in Cumulus Cells and Oocyte Quality Paolo Giovanni Artini1 (1) Division of Gynecology and Obstetrics, Department…
© International Society of Gynecological Endocrinology 2016Andrea R. Genazzani and Basil C. Tarlatzis (eds.)Frontiers in Gynecological EndocrinologyISGE Series10.1007/978-3-319-23865-4_8 8. The Long-Term Risks of Premature Ovarian Insufficiency Andrea Giannini1, Andrea R. Genazzani1 and Tommaso Simoncini1 (1) Division of Obstetrics and…
© International Society of Gynecological Endocrinology 2016Andrea R. Genazzani and Basil C. Tarlatzis (eds.)Frontiers in Gynecological EndocrinologyISGE Series10.1007/978-3-319-23865-4_12 12. Androgen Replacement in Women: Safe and Efficacious? Nicholas Panay1 (1) Department of West London Menopause Service, Nick…
© International Society of Gynecological Endocrinology 2016Andrea R. Genazzani and Basil C. Tarlatzis (eds.)Frontiers in Gynecological EndocrinologyISGE Series10.1007/978-3-319-23865-4_6 6. Biomarkers of Ovarian Ageing Paolo Giovanni Artini1 (1) Division of Gynecology and Obstetrics, Department of Experimental and Clinical…
Nephroprotection Decreased inflammation Antiproteinuric effect Increased nephrin expression Suppression of renin, RR, AT II Decreased NF-κB activation Anti EGFR signaling? Glucose metabolism Increased insulin secretion Increased insulin sensitivity Increased glucose…
Fig. 13.1 Plasma ratio (40:1) and pharmacokinetics of MI and DCI. Data of two different studies in human volunteers Recently, three different studies evaluated the efficacy of a treatment based…
