© Springer Science+Business Media New York 2015Lisa A. Newman and Jessica M. Bensenhaver (eds.)Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer10.1007/978-1-4939-2035-8_16 16. Introduction, Evolution, and Application of the Van Nuys Prognostic Index in DCIS Aeisha…
Fig. 14.1 Baseline and follow-up mammograms in a 51-year-old woman with initial diagnosis of DCIS, treated with breast-conserving surgery and adjuvant radiation. Left breast mammogram at initial diagnosis and at…
(1) Department of Radiation Oncology, University of Michigan Health System, 1500 East Medical Center Drive, 48109 Ann Arbor, MI, USA Corey W. Speers Email: rjagsi@med.umich.edu KeywordsDCISMastectomyRadiationLocal recurrenceBreast cancerDecision makingRadiation side…
Consensus group Definition of negative margin Additional recommendations The American Society of Breast Surgeons [19] No ink on tumor No further surgery if margins > 1 mm, consider re-excision on a case-by-case…
Proliferation genes Ki-67 Higher Ki-67 is seen in poorly differentiated DCIS; an increase in Ki-67 is associated with invasion [22, 23] STYKI5 Loss of overexpression is associated with progression from…
Author Number of patients with DCIS in whom SLN biopsy was performed Number (%) of patients with positive SLN Klauber De More [3] 72 5 (7 %) Wilkie [4] 559 27…
© Springer Science+Business Media New York 2015Lisa A. Newman and Jessica M. Bensenhaver (eds.)Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer10.1007/978-1-4939-2035-8_10 10. Anti-HER2/neu Therapy in DCIS Amelia Tower1 , Ruta D. Rao3 , Kalliopi P. Siziopikou2, 4 , Melody A. Cobleigh3 and…
Year published Patients Years treated Follow-up (months) Local recurrence rate (%) Randomized Non-randomized NSABP B-17 2011 411 1985–1990 206 19.8 (15 years) EORTC 10853 2013 507 1986–1996 128 18…
© Springer Science+Business Media New York 2015Lisa A. Newman and Jessica M. Bensenhaver (eds.)Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer10.1007/978-1-4939-2035-8_8 8. Ductal Carcinoma In Situ Treated with Breast-Conserving Surgery Alone Jessica M. Bensenhaver1 (1) University…
Study Initial biopsy period # cases F/U (years) # subsequent invasive cancers (%) Betsill et al. [11] 1940–1950 10 21.6 6 (60 %) Rosen et al. [10] (expansion of Betsill study)…
