Management of Conn’s Syndrome

Feb 26, 2017 by in ENDOCRINOLOGY Comments Off on Management of Conn’s Syndrome

Causes of primary hyperaldosteronism Percentage of cases Remarks Aldosterone-producing adenoma (APA) ~35 % Original pathology described by Conn Bilateral idiopathic adrenal hyperplasia (BAH) ~60 % – Primary unilateral adrenal hyperplasia…

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Adrenal Metastasectomy

Feb 26, 2017 by in ENDOCRINOLOGY Comments Off on Adrenal Metastasectomy

Pearls Pitfalls All patients should be discussed in a multidisciplinary team (MDT) meeting Be sure that the imaging is contemporaneous as some adrenal metastases have a rapid doubling time (esp…

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Cushing’s Disease and Syndrome

Feb 26, 2017 by in ENDOCRINOLOGY Comments Off on Cushing’s Disease and Syndrome

Fig. 2.1 Contrast-enhanced CT scan in a patient with Cushing’s syndrome demonstrating a left primary adrenal tumor and a synchronous metastasis in the right lobe of the liver Medical Management…

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Adrenocortical Carcinoma and Open Adrenalectomy

Feb 26, 2017 by in ENDOCRINOLOGY Comments Off on Adrenocortical Carcinoma and Open Adrenalectomy

Histological criteria assessed for the Weiss score High mitotic rate Atypical mitoses High nuclear grade Low percentage of clear cells Necrosis Diffuse architecture of tumor Capsular invasion Sinusoidal invasion Venous…

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Adrenal Tumors

Feb 18, 2017 by in ONCOLOGY Comments Off on Adrenal Tumors

Hereditary Tumor Syndrome Manifestation of Tumor Gene (chromosomal locus) Syndrome Prevalence of ACT Li-Fraumeni TP53 (17p13), hCHK2 (22q12.1), lq23 Soft tissue sarcoma, osteosarcoma, breast cancer, brain tumor, leukemia, ACC ACC,…

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Pancreatic Cystic Tumors

Feb 18, 2017 by in ONCOLOGY Comments Off on Pancreatic Cystic Tumors

Injury-related and inflammation-related cysts (30%)   • Pseudocyst • Paraduodenal wall cyst • Infection-related cysts Neoplastic cysts (60%)   Ductal lineage   Mucinous type (30%)   • Intraductal papillary mucinous…

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Non-invasive and Invasive Breast Cancer

Feb 18, 2017 by in ONCOLOGY Comments Off on Non-invasive and Invasive Breast Cancer

Fig. 14.1 Possible intraductal and discontinuous peritumoral spread of DCIS These issues warrant thorough preoperative assessment (usually breast MRI). Most DCIS are non-palpable lesions (mostly microcalcifications) so careful preoperative localization…

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Pancreatic Adenocarcinoma

Feb 18, 2017 by in ONCOLOGY Comments Off on Pancreatic Adenocarcinoma

Fig. 6.1 Axial contrast-enhanced arterial phase MDCT demonstrates dilatation of the distal common bile duct (*) due to isoattenuating adenocarcinoma (arrow) of the pancreatic head. The main pancreatic duct of…

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Hepatobiliary Cancer

Feb 18, 2017 by in ONCOLOGY Comments Off on Hepatobiliary Cancer

Fig. 5.1 A large HCC in a 75-year-old HCV-positive patient treated by selective internal radiation treatment (SIRT). (a) Angiographic image during SIRT. (b) CT after SIRT. (c) The specimen after…

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Pulmonary Malignancies

Feb 18, 2017 by in ONCOLOGY Comments Off on Pulmonary Malignancies

Fig. 15.1 The da VinciTM robotic system (courtesy of Surgical Intuitive, Inc., Sunnyvale, CA, USA) Instruments EndoWrist instruments are designed to provide surgeons with natural dexterity and a full range…

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