Figure 20.1 Pedigree of family with myeloproliferative neoplasm. Filled symbols indicate affected individuals. The Roman numerals represent generation and the Greek numeral stands for the individual family member. PV, polycythemia…
Figure 10.1 Survival estimates from diagnosis of primary myelofibrosis patients who become intermediate-2 and high-risk International Prognostic Score System (IPSS) with a blast cell count <10% at any time of…
Figure 19.1 Challenging thrombosis scenarios. MPN, myeloproliferative neoplasm; APC, activated protein C resistance. As reviewed in: Falanga A, Marchetti M. Thrombosis in myeloproliferative neoplasms. Semin Thromb Hemost. 2014;40(3):348–58. Adapted from:…
html xmlns=”http://www.w3.org/1999/xhtml” xmlns:mml=”http://www.w3.org/1998/Math/MathML” xmlns:epub=”http://www.idpf.org/2007/ops”> 18 Managing acute vascular events in patients with myeloproliferative neoplasms David A. Garcia and Bethany T. Samuelson Case 1 A 62-year-old man is referred to hematology…
Figure 17.1 Local management protocol. FBC, full blood count; BP, blood pressure; PV, polycythemia vera. There are no controlled studies regarding pregnancy outcome. As such there are no validated predictors…
+8, –7/7q–, –5/5q–, i17q, 12p–, 11q23 rearr.+1 point each1 point each (Hb: 2 points)DIPSS int-1: 1 pointDIPSS int-2: 2 pointsDIPPS high: 3 pointsPlatelets < 100 × 109/L, unfavorable karyotype, transfusion…
Figure 13.1 Diagnostic algorithm for hypereosinophilia and treatment options based on each subtype. FISH, fluorescent in situ hybridization; RT-PCR, reverse transcriptase polymerase chain reaction; NOS, not otherwise specified; WHO, World…
1 is most favorable and 10 least favorablePlease rate your fatigue (weariness, tiredness) by circling the one number that best describes your worst level of fatigue during past 24 hoursa(No…
Manage scenarios associated with increased risk, e.g., surgery, pregnancy The most important direct way of assessing compliance is through patient interview.2 Other measures, such as direct observation of medication intake,…
Figure 7.1 Flow chart of recommendations for the management of patients with essential thrombocythemia (ET). CV, cardiovascular; HU, hydroxyurea; WHO, World Health Organization. Intervention on lifestyle Thrombosis is a multifactorial…
