Pathogenesis of Gastric Cancer

Jun 4, 2017 by in ONCOLOGY Comments Off on Pathogenesis of Gastric Cancer

Fig. 6.1 Precursor lesion of intestinal type gastric cancer – dysplasia. (a) Low-grade dysplasia. Pseudostratification of nuclei. Nuclei are elongated and mostly basally orientated. Few mitotic figures. (b) High-grade dysplasia….

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Multimodality Therapy in Gastric Cancer

Jun 4, 2017 by in ONCOLOGY Comments Off on Multimodality Therapy in Gastric Cancer

Treatment arms Primary end point Secondary end points MAGIC [3] Surgery alone Epirubicin 50 mg/m2 day 1 5-year OS 5-year PFS Cisplatin 60 mg/m2 day 1 HR 0.75 HR 0.66…

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Pathogenesis of Esophageal Cancer

Jun 4, 2017 by in ONCOLOGY Comments Off on Pathogenesis of Esophageal Cancer

Risk factor Risk Tobacco 4–8× Alcohol 1.3–8× Alcohol dehydrogenase 4× Fruits and vegetables 0.53–0.56× Poverty 8× Gastroesophageal reflux 7.7× Obesity 3.1× Helicobacter pylori infection 0.56–1.1× Squamous Cell Carcinoma Worldwide squamous…

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