Oncohema Key

Tumor classification Definition Stage Criteria T0, N0, M0 Not found Stage I T1 T1 One nodule <2.0 cm Stage II T2 T2 One nodule 2.0–5.0 cm; 2 or 3 nodules, all <3.0 cm Stage III T3 T3…

  Without underlying liver disease With underlying liver disease p value Number 82 124 − Liver disease, n (%) HBV (HBsAg+) HCV (anti-HCV Ab+) NASH Alcoholic liver disease Other −…

Fig. 1 Algorithm for management of transplantable hepatocellular carcinoma at Henri Mondor Hospital, Creteil, France [3] For patients with a solitary HCC<5 cm, no evidence of extrahepatic tumor burden, compensated liver disease,…

Classification Stages/Scores Parameters Survival/Stage (%) Hepatitis (%)  Study area of origin Tumor characteristics Liver function Health status Hepatitis B Hepatitis C Both Okuda I, II, III </>50 % liver involvement Bilirubin,…

Characteristic TheraSphere® SIR-Sphere® Isotope 90Y 90Y Half-Life (h) 64.2 64.2 Particle Size (μm) 20–30 20–60 Range of spheres per vial 1.2–8.0 million 40–80 million Activity per sphere (Bq) 2500 50…

Stage AJCC- clinical staging AJCC-staging I 81 (51 %) 60 (38 %) II 57 (36 %) 49 (31 %) III 7 (4 %) 9 (6 %) IV 0 1 (0.6 %) No lesions 14 (9 %) 12 (7 %)…

Fig. 1 Treatment algorithm of patients with HCC based on serum bilirubin level and indocyanine green retention rate at 15 min. Adapted from Makuuchi et al. [8] 2.3 Assessment of the Future…

Chemical ablation    – Ethanol injection   Thermal ablation    – Radiofrequency ablation  – Microwave ablation  – Laser ablation  – Cryoablation   Irreversible electroporation   2 Chemical Ablation The seminal…

Fig. 1 Macroscopic aspects of Hepatocellular carcinoma: a Nodular pattern of HCC developed in a cirrhotic liver. b Infiltrative pattern of HCC developed in a cirrhotic liver. c Early HCC (progressed…

Fig. 1 Cell signalling pathways implicated in hepatocarcinogenesis Overexpression of HGF and c-MET occurs in 33 and 20–48 % of human HCC tumors, respectively [41–45] and appears to be associated with earlier…