Clinical syndrome Commonly associated fungi Therapy Onychomycosis Onychocola, Alternaria Itraconazole or terbinafine Subcutaneous nodules Exophiala, Alternaria, Phialophora Surgery ± itraconazole or voriconazole Keratitis Curvularia, Bipolaris, Exserohilum, Lasiodiplodia Topical natamycin ±…
Genus/Species AmB Itraconazole Voriconazole Posaconazole Anidulafungin Caspofungin Micafungin Ref. Fusarium spp. F. oxysporum F. solani ++ ++ + + + + ++b ++++ + ++ ++ + 0 ND ND…
Trichosporon T. asahii (T. beigelii) T. inkin T. mucoides Saccharomyces S. cerevisiae S. boulardii Rhodotorula R. mucilaginosa (rubra) R. glutinis Malassezia M. furfur M. pachydermati Blastoschizomyces capitatus (Geotrichum capitatum, Trichosporon…
Fig. 3.1 The relationship between yield, number of steps, and type of fungal template preparation method. The greatest yield comes from laborious methods that require numerous steps, including organic extractions….
Fig. 10.1 Microscopic morphology of Aspergillus fumigatus showing a single role of phialides (uniseriate) bearing smooth conidia in a columnar fashion. (Courtesy of www.doctorfungus.org) Table 10.1 Characteristics of common Aspergillus…
Fig. 14.1 Silver-stained bronchoalveolar lavage specimen showing characteristic clusters of Pneumocystis cysts As noted above, the host-species specificity of Pneumocystis has led some to propose the division of Pneumocystis carinii…
Fluconazole Itraconazole Flucytosine Amphotericin B Voriconazole Posaconazole Echinocandins Candida species C. albicans S S S S S S S C. tropicalis S S S S S S S C….
CD4+ T lymphocyte cell count (cells/µl) Fungal infections > 500 Candidal vaginitis 200–500 Thrush (oropharyngeal candidiasis) < 200 PCP, disseminated histoplasmosis, disseminated coccidioidomycosis < 100 Cryptococcosis, candidal esophagitis, penicilliosis PCP Pneumocystis pneumonia Organ…
Population Assay Study design Sensitivity(%) Specificity(%) Commentsb Ref. All Any Meta-analysis of 16 studies: 2979 patients; 594 with proven/probable IFI. Excluded diagnosis of PCP 77 85 One positive test required;…
Fig. 3.1 CT scan in a patient with urachal cancer through the upper abdomen showing large volume disease in the right upper quadrant, left upper quadrant, and lesser omentum (From…
