The Role of Hormonal Treatment in Prostate Cancer
Study No of patients Randomization Results RTOG 85-31 [31] 977 RT vs. RT + LHRHa (continuous) Combined arm is better in all end points RTOG 86-10 [32] 456 RT vs. RT + 4 month CAB…
Adjuvant or Salvage Radiotherapy in Postoperative Prostate Cancer
© Springer International Publishing AG 2017Gokhan Ozyigit and Ugur Selek (eds.)Principles and Practice of Urooncologyhttps://doi.org/10.1007/978-3-319-56114-1_17 17. Adjuvant or Salvage Radiotherapy in Postoperative Prostate Cancer Ugur Selek1, 2, Yasemin Bolukbasi1, 2 and Deborah A. Kuban2 (1) Department of Radiation Oncology,…
Targeted Therapies and ImmunotherapyImmunotherapyin bladder cancer in Bladder Cancer
© Springer International Publishing AG 2017Gokhan Ozyigit and Ugur Selek (eds.)Principles and Practice of Urooncologyhttps://doi.org/10.1007/978-3-319-56114-1_6 6. Targeted Therapies and Immunotherapy in Bladder Cancer Mehmet Ali Nahit Şendur1 and Sercan Aksoy2 (1) Department of Medical Oncology, Ankara Yıldırım Beyazıt University,…
Modeling Cancer Metastasis
Fig. 7.1 A model of PCa progression. PCa starts as a localized tumor. In its natural progression, it typically metastasizes to the lymph nodes and then the bone, producing bone-forming…
Using PDX for Biomarker Development
Fig. 9.1 Biomarker Classification. Adapted from Mishra A, Verma M. Cancer biomarkers: are we ready for the prime time? Cancers. 2010;2(1):190–208. doi:10.3390/cancers2010190 DNA Biomarkers The most fundamental event in the…
Patient-Derived Tumor Xenografts: Historical Background
© Springer International Publishing AG 2017Yuzhuo Wang, Dong Lin and Peter W. Gout (eds.)Patient-Derived Xenograft Models of Human Cancer Molecular and Translational Medicine10.1007/978-3-319-55825-7_1 1. Patient-Derived Tumor Xenografts: Historical Background Dong Lin1, 2, 3 , Xinya Wang1, Peter W. Gout4, 3 and…
Towards Best Practice in Establishing Patient-Derived Xenografts
Fig. 2.1 Overview of the main steps in establishing PDXs. Step 1: High-quality patient specimens are obtained from various stages of cancer progression, from benign tissue to metastases, using a…
Studies of Cancer Heterogeneity Using PDX Models
Fig. 5.1 Efficacy study of S-1 in four gastric PDX models. a and b show that GAPF155 and GAPF157 were sensitive to S-1; c and d show that GAPF161 and…
Pathologic Diagnosis of Thyroid Cancer
Fig. 4.1 Overturning the aspiration needle and tapping the material on the slide can often facilitate removal of partially clotted specimen in the needle hub Once a small amount of…
Lymph Node Dissection for Differentiated Thyroid Cancer
Fig. 13.1 (a) Lymph node groups in the neck. From Fialkowski EA, Moley JF. Current approaches to medullary thyroid carcinoma, sporadic, and familial. (b) Specimen from a patient following central…
