Fig. 10.1 Incidence and mortality age standardized rate of ovarian cancer according to United Nations world regions in 2012 (United Nations 2014) There are several factors that increase the risk…
Fig. 8.1 Age standardised incidence and mortality of top 10 cancers in sub-Saharan African women compared to Europe in 2012 (GLOBOCAN 2012) Within SSA, there is a wide variation in…
Phase Normal, adaptive Abnormal, maladaptive Pre-diagnosis Concern about the possibility of having cancer Hyper-vigilance Inappropriate preoccupation Development of cancer symptoms without having the disease Diagnosis Shock Disbelief Initial, partial denial…
© Springer International Publishing AG 2017Olufunso Adebola Adedeji (ed.)Cancer in Sub-Saharan Africa10.1007/978-3-319-52554-9_11 11. Delivering Safe and Affordable Cancer Surgical Care Rotimi A. K. Jaiyesimi1, 2, 3 and Ayo Oshowo4, 5 (1) Department of Obstetrics and Gynaecology, Basildon and…
Fig. 2.1 The age standardised incidence rate of the most common cancers in (a) females and (b) males in SSA (Source: GLOBOCAN 2012 (IARC)) 2.1.1 Environmental Factors Inter and intra-regional…
Fig. 4.1 Healthcare spending as percentage of GDP Fig. 4.2 Healthcare spending as percentage of total government expenditure There is extreme shortage of pathologists in SSA. The tertiary institutions with…
Fig. 5.1 Continuum of translational research (Khoury et al. 2010; Glasgow et al. 2012) T0 scientific discovery research, T1 translational research from discovery to candidate application, T2 translational research from…
Chromosomal translocations Genes Comments Involving RARAα t(15;17)(q21;q21) PML DNA binding, cell proliferation RARα Transcription factor t(11;17)(q23;q21) ZBTB16 (PLZF) Zn-finger transcription factor RARα Transcription factor t(5;17)(q32;q21) NPM1 RNA transport/processing RARα Transcription…
(1) Department of Patholog, University of Massachusetts Medical School, Baystate, Springfield, MA, USA (2) Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine, Chapel Hill, NC,…
Fig. 1.1 Cancer incidence and mortality by site for both sexes (USA, 2015). The relative contributions of the major forms of cancer to overall cancer incidence and cancer-related mortality (both…
