Immunology and Immunotherapy in Ovarian Cancer

Oct 14, 2017 by in ONCOLOGY Comments Off on Immunology and Immunotherapy in Ovarian Cancer

Specificity activation Non-specific (activate systemic immunity, relatively old) Specific (target cancer cells or cancer-specific antigens, relatively old) Active immunization (to elicit immunity in vivo) Biological response modifier Cancer vaccine Dendritic…

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Strategies for the Management of Non-epithelial Ovarian Tumors

Oct 14, 2017 by in ONCOLOGY Comments Off on Strategies for the Management of Non-epithelial Ovarian Tumors

Fig. 10.1 Treatment of malignant sex cord-stromal tumors. *Fertility-preserving surgery—affected-side salpingo-oophorectomy + omentectomy + peritoneal cytology + detailed intra-abdominal examination. **Lymph node dissection (biopsy) can be omitted. Reprint with permission from ref. 21 10.3 Malignant Ovarian…

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Management of Ovarian Cancer in the Elderly Population

Oct 14, 2017 by in ONCOLOGY Comments Off on Management of Ovarian Cancer in the Elderly Population

Fig. 16.1 Cycle of frailty [66], reprinted with permission of Oxford University Press Fig. 16.2 Hypothesized molecular and physiological association with frailty [67], reprinted with permission of John Wiley and…

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Treatment of Recurrent Epithelial Ovarian Cancer

Oct 14, 2017 by in ONCOLOGY Comments Off on Treatment of Recurrent Epithelial Ovarian Cancer

Fig. 14.1 Treatment strategy of recurrent epithelial ovarian cancer Table 14.1 Important clinical trials for recurrent ovarian cancer Study (y) Drug n Primary endpoint RR(%) PFS(M) OS(M) Comments Platinum-sensitive disease…

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Hereditary Ovarian Cancer

Oct 14, 2017 by in ONCOLOGY Comments Off on Hereditary Ovarian Cancer

  High-grade serous Low-grade serous High-grade endometrioid Low-grade endometrioid Clear cell Mucinous Unspecified carcinoma No. 1501 70 64 14 58 16 166 BRCA1 (%) 10.3 4.3 6.3 0 6.9 0…

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