Blood cancers begin in the bone marrow or immune system and affect how blood cells grow and function. These cancers often develop silently, with symptoms that may go unnoticed until…
Hysterectomy is one of the most commonly performed gynecologic surgeries worldwide. It is often recommended for conditions such as fibroids, endometriosis, uterine prolapse, or malignancy. According to the Centers for…
Highlights • Small molecule MIF inhibitor CPSI-1306 inhibits HNSCC growth in vivo . • CPSI-1306 potently inhibits T cell immunosuppression in the tumor microenvironment. • CPSI-1306 completely abrogates CTLA4, TIGIT…
Highlights • The immune TME in NPC is unsupervisedly dissected into “Immune Inflamed” and “Immune Deficient” subtypes. • Tertiary lymphoid structures (TLS) serve as better prognostic indicators than individual immune…
Highlights • ctDNA provided complementary information on actionable mutations to tissue biopsy. • ctDNA provided a comprehensive view of mutational landscape dynamics over time. • ctDNA-based molecular relapse detection has…
Highlights • Omitting prophylactic PEG and younger age associated with increased weight loss. • Higher risk of feeding tube duration with prophylactic PEG and older patients. • Prophylactic PEG did…
We wish to address the article entitled “Evaluation of the 10 %-rule in sentinel lymph node biopsy for clinically node-negative oral squamous cell carcinoma” by Tellman et al. . While the…
Highlights • Lymph node metastasis with extranodal extension was the most important prognostic factor. • Postoperative radiotherapy was associated with a lower risk of recurrence and a good prognosis. •…
Highlights • This study is the first to explore the efficacy and safety of the docetaxel, cisplatin, and capecitabine (TPC) regimen compared to GP and TPF. • Our findings indicate…
Highlights • The 10%-rule effectively identified metastatic sentinel nodes intraoperatively. • Applying the 10%-rule per neck side must be considered. • Raising the threshold is not advised, as this leads…
