Quantification of micropapillary component on transurethral resection is associated with likelihood of occult lymph node metastasis at radical cystectomy

May 11, 2025 by in ONCOLOGY Comments Off on Quantification of micropapillary component on transurethral resection is associated with likelihood of occult lymph node metastasis at radical cystectomy

Highlights • Micropapillary Urothelial Carcinoma (MPUC) is associated with poor oncologic outcomes. • Unknown whether greater fraction of MPUC component is prognostically relevant. • Largest ever pathologic review and quantification…

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5α-reductase inhibitors with or without alpha-blockers and risk of incident upper tract urothelial carcinoma in men with benign prostatic hyperplasia: Analysis of US insurance claims data

May 11, 2025 by in ONCOLOGY Comments Off on 5α-reductase inhibitors with or without alpha-blockers and risk of incident upper tract urothelial carcinoma in men with benign prostatic hyperplasia: Analysis of US insurance claims data

Highlights • The effect of 5-alpha reductase inhibitors on upper tract urothelial carcinoma has not been explored. • Men taking 5-alpha reductase inhibitors were identified using Merative TM Marketscan®. •…

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Comparing direct medical care costs of patients with bladder cancer who received an ileal conduit vs. neobladder in the year following cystectomy

May 11, 2025 by in ONCOLOGY Comments Off on Comparing direct medical care costs of patients with bladder cancer who received an ileal conduit vs. neobladder in the year following cystectomy

Highlights • Mean medical care costs in the year following radical cystectomy were similar between bladder cancer patients who received an ileal conduit and those who received a neobladder. •…

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Tumor involvement of the trigone and urethra at the time of robot-assisted radical cystectomy is associated with adverse oncological outcomes

May 11, 2025 by in ONCOLOGY Comments Off on Tumor involvement of the trigone and urethra at the time of robot-assisted radical cystectomy is associated with adverse oncological outcomes

Highlights • Residual tumor involvement in the trigone and urethra after radical cystectomy is associated with a higher tumor stage, and positive margins. • It was significantly associated with tumor…

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State of the Art: The Microbiome in Bladder Cancer

May 11, 2025 by in ONCOLOGY Comments Off on State of the Art: The Microbiome in Bladder Cancer

Abstract This review assesses the current understanding of the relationship between the human microbiome and BCa. Recognizing how the microbiome affects the tumor microenvironment provides valuable insights into cancer biology,…

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