Rethinking the definition of stage III disease in adrenocortical carcinoma: Assessing the impact of clinical lymph node positive disease

May 11, 2025 by in ONCOLOGY Comments Off on Rethinking the definition of stage III disease in adrenocortical carcinoma: Assessing the impact of clinical lymph node positive disease

Abstract Introduction Stage III adrenocortical carcinoma encompasses both lymph node positive (TanyN1M0) and negative (T3-4N0M0) disease. Given the disease’s rarity, the current staging paradigm’s estimates of survival are supported by…

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Investigating the pattern of prostate specific antigen screening among E-cigarette smokers within the behavioral risk factor surveillance system

May 11, 2025 by in ONCOLOGY Comments Off on Investigating the pattern of prostate specific antigen screening among E-cigarette smokers within the behavioral risk factor surveillance system

Highlights • E-cigarette users are less likely to undergo PSA screening than never-smokers and tobacco smokers. • This pattern of PSA screening utilization among e-cigarette users may be attributed to…

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Genetic variations related to the prostate cancer risk: A field synopsis and revaluation by Bayesian approaches of genome-wide association studies

May 11, 2025 by in ONCOLOGY Comments Off on Genetic variations related to the prostate cancer risk: A field synopsis and revaluation by Bayesian approaches of genome-wide association studies

Highlights • The calculations showed specific SNPs at 8q24 locus as noteworthy for PCa risk. • The MSMB, ITGA6, SUN2, FGF10, INCENP, MLPH, and KLK3 genes were noteworthy for PCa….

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Causal relationship between bladder cancer and gut microbiota contributes to the gut-bladder axis: A two-sample Mendelian randomization study

May 11, 2025 by in ONCOLOGY Comments Off on Causal relationship between bladder cancer and gut microbiota contributes to the gut-bladder axis: A two-sample Mendelian randomization study

Highlight • Five gut microbiota were found to be causally associated with bladder cancer. • Among these taxa, the genus Bilophila was identified as having a promoting effect on bladder…

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The use of nephron-sparing intervention does not appear to be compromised after a period of active surveillance for patients with cT1 renal masses

May 11, 2025 by in ONCOLOGY Comments Off on The use of nephron-sparing intervention does not appear to be compromised after a period of active surveillance for patients with cT1 renal masses

Highlights • We compared treatments in patients with cT1 renal masses undergoing immediate vs delayed intervention. • Use of nephron sparing interventions were not compromised by a period of active…

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Prognostic significance of body mass index in patients with metastatic renal cell carcinoma receiving first-line therapies

May 11, 2025 by in ONCOLOGY Comments Off on Prognostic significance of body mass index in patients with metastatic renal cell carcinoma receiving first-line therapies

Highlights • Overweight patients with metastatic renal cell carcinoma had an overall survival advantage following first-line therapies. • Obesity paradox may exist in the contemporary cancer immunotherapy era for metastatic…

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Long-term oncologic outcomes and complications of robot-assisted radical cystectomy for the treatment of urothelial carcinoma of the bladder

May 11, 2025 by in ONCOLOGY Comments Off on Long-term oncologic outcomes and complications of robot-assisted radical cystectomy for the treatment of urothelial carcinoma of the bladder

Highlights • Largest single tertiary center RARC series with the longest follow-up in the U.S. • Extravesical disease and lymph node positivity affect OS and RFS long-term. • Infection and…

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Laparoscopic suture-free partial nephrectomy using argon-beam-coagulator: Surgical technique and outcomes of a single-center, open-label randomized controlled trial

May 11, 2025 by in ONCOLOGY Comments Off on Laparoscopic suture-free partial nephrectomy using argon-beam-coagulator: Surgical technique and outcomes of a single-center, open-label randomized controlled trial

Highlights • Suture-free PN is a safe and feasible technique for T1a renal masses. • Suture-free PN benefits short-term and long-term SRF and eGFR compared to conventional Suture PN. Abstract…

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