Retrospective analysis of partial cystectomy in patients with muscle-invasive urothelial carcinoma: A German single-center experience

May 11, 2025 by in ONCOLOGY Comments Off on Retrospective analysis of partial cystectomy in patients with muscle-invasive urothelial carcinoma: A German single-center experience

Highlights • Partial cystectomy serves as a less invasive alternative for muscle-invasive bladder cancer. • The 5-year Overall Survival rate was 55%, Cancer Specific Survival was 67%, and Recurrence-Free Survival…

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Defining the genetic profile of prostate cancer

May 11, 2025 by in ONCOLOGY Comments Off on Defining the genetic profile of prostate cancer

Highlights • Prostate cancer is associated with the genetic components. • The understanding of the genetics components of prostate cancer will help researchers in developing mitigating approach. • GWAS provides…

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Impact of postprogression therapies on overall survival: Recommendations from the 2023 kidney cancer association think tank meeting

May 11, 2025 by in ONCOLOGY Comments Off on Impact of postprogression therapies on overall survival: Recommendations from the 2023 kidney cancer association think tank meeting

Highlights • Accounting for postprogression therapies improves overall survival (OS) estimation. • Multistage treatment strategies (MTS) guide treatment sequence decisions to optimize OS. • Sequentially Multiple Assignment Randomized Trials (SMART)…

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Prospective validation of clino-radio-pathological risk scoring system (CRiSS) for prediction of inguinal lymph-nodes metastasis in squamous cell carcinoma of penis

May 11, 2025 by in ONCOLOGY Comments Off on Prospective validation of clino-radio-pathological risk scoring system (CRiSS) for prediction of inguinal lymph-nodes metastasis in squamous cell carcinoma of penis

Highlights • A prospective study to validate the diagnostic performance of CRiSS in SCC penis. • CRiSS can avoid ILND with a zero false negative rate, irrespective of cN status….

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Clinical significance of PSA dynamics in castration-sensitive prostate cancer treated with ARSI doublet therapy: A multicenter study

May 11, 2025 by in ONCOLOGY Comments Off on Clinical significance of PSA dynamics in castration-sensitive prostate cancer treated with ARSI doublet therapy: A multicenter study

Highlights • The addition of androgen receptor signaling inhibitors (ARSIs) to androgen deprivation therapy (ADT), known as ARSI doublet therapy, has shown a significant impact on PSA dynamics and oncological…

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Patient-reported functional outcomes and treatment-related regret in Hispanic and Spanish-speaking men following prostate cancer treatment

May 11, 2025 by in ONCOLOGY Comments Off on Patient-reported functional outcomes and treatment-related regret in Hispanic and Spanish-speaking men following prostate cancer treatment

Highlights • Spanish-speaking Hispanic men had no long-term adverse outcomes despite lower SES. • English-speaking Hispanic men reported higher levels of treatment-related regret. • Spanish surveys may reflect language concordant…

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Perioperative outcomes, environmental impact and economic implications of pelvic drain discontinuation in prostate cancer patients undergoing robot-assisted radical prostatectomy

May 11, 2025 by in ONCOLOGY Comments Off on Perioperative outcomes, environmental impact and economic implications of pelvic drain discontinuation in prostate cancer patients undergoing robot-assisted radical prostatectomy

Highlights • Discontinuing pelvic drain (PD) placement after RARP did not increase the risk of overall or high-grade complications. • Patients without PD required fewer opioids, indicating better postoperative pain…

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Development of prediction models based on risk scores for clinically significant prostate cancer on MRI/TRUS fusion biopsy

May 11, 2025 by in ONCOLOGY Comments Off on Development of prediction models based on risk scores for clinically significant prostate cancer on MRI/TRUS fusion biopsy

Highlights • Predicting models may reduce unnecessary biopsies and optimize its indication. • Risk Scores have shown to work as reliable and ease to use predicting models. • Combining age,…

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