Drug holidays
Learning objectives • “Drug holidays” refer to the discontinuation—temporary or permanent—of bisphosphonate therapy following a 3- to 5-year period of continuous therapy whether oral or IV. • Determine whether to…
Zoledronic acid—Annual infusions
Learning objectives • Osteoporosis is silent until a fracture is sustained. • Osteoporosis is underdiagnosed and undertreated. • The pharmacologic profile of zoledronic acid: efficacy and adverse effects. The case…
Oral bisphosphonates—Lack of response
Learning objectives • Evaluation of patients on long-term bisphosphonate therapy for drug resistance. • Recognize lifestyle habits that can interfere with bisphosphonate efficacy. The case study Reasons for seeking medical…
Oral bisphosphonates—Long term: 13 years
Learning objectives • Evaluation of patients on long-term antiresorptive therapy. • When and how to discontinue long-term bisphosphonate therapy. The case study Reasons for seeking medical help • VP is…
Oral bisphosphonates—Drug holidays and discontinuing therapy
Learning objectives • Monitor patients on long-term antiresorptive therapy. • Determine whether to continue or discontinue long-term antiresorptive therapy. • Determine whether a “Drug holiday” is appropriate in the management…
Oral bisphosphonates—Initiating and maintaining treatment
Learning objectives • The pharmacology profile of orally administered bisphosphonates. • Initiating and maintaining pharmacologic treatment with oral bisphosphonates. The case study Reason for seeking medical help • BJ, a…
Screening for osteoporosis
Learning objectives • The importance of screening for osteoporosis. • Risk factors predisposing to osteoporosis. • Who, when, and how to screen for osteoporosis. • Unnecessary laboratory and imaging studies…
Osteopenia: Individualizing treatment—Part IV
Learning objectives • Individualizing the management strategy for patients with osteopenia and low fracture risk. • Know when to override the results of the FRAX score and NOF recommendations. •…
Osteopenia: Individualizing treatment—Part III: When silent vertebral compression fractures override the densitometric diagnosis
Learning objectives • The integration of DXA scan results, FRAX algorithm score, NOF guidelines, and patient’s clinical condition to develop a management strategy tailored to the individual circumstances of the…
Osteopenia: Individualizing treatment—Part II
Learning objective • Integrate clinical findings, DXA scan results, FRAX results, and NOF guidelines to develop a management strategy tailored to the individual needs of the particular patient concerned. The…
